Reproducibility of Acute Caffeine Effect
- Conditions
- Caffeine and Resistance Exercise
- Interventions
- Dietary Supplement: CaffeineDietary Supplement: Placebo
- Registration Number
- NCT06606639
- Lead Sponsor
- University of Alcala
- Brief Summary
Introduction: Various studies have evaluated and verified the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, all experimental investigations designed so far have been based on the comparison of the \"caffeine\" and \"placebo\" conditions in a single trial, not considering the reproducibility and variability of caffeine in multiple trials.
Objectives: The present study aims to evaluate the reproducibility and replicability of the acute effect of caffeine intake on energy metabolism and the muscular production of force, power and endurance, according to sex (men vs women) and type of exercise ( bench press vs squat).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 48
- Age between ≥ 18 and ≤ 35 years.
- Body Mass Index (BMI) < 25 kg/m².
- Resistance-trained individuals (> 2 years of structured trained).
- Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
- Participants must be able to perform the tests described in the following section.
- History of neuromuscular diseases, heart diseases, or diseases that may affect liver or muscle metabolism.
- Use of drugs, other stimulants or sport supplements that interfere with the the study dietary supplement.
- Sedentary habits (<150 min/week of moderate exercise).
- Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
- Performing strenuous exercise during the 48 hours prior to the tests.
- Failure to replicate the same food intake on the two days of the experiments.
- Consuming caffeine or any other stimulant after 6 pm the day before the training or tests, to avoid headaches, discomfort, or lethargy among regular caffeine consumers.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Caffeine - Trial 1 Caffeine - Caffeine - Trial 2 Caffeine - Caffeine - Trial 3 Caffeine - Placebo - Trial 1 Placebo - Placebo - Trial 2 Placebo -
- Primary Outcome Measures
Name Time Method Mean velocity at different %1RM Through study completion, an average of 4 weeks Measuring bar mean velocity desplacement during bench press and back squat exercises.
Peak velocity at different %1RM Through study completion, an average of 4 weeks Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.
Mean power output at different %1RM Through study completion, an average of 4 weeks Measuring during bench press and back squat exercises.
Peak power output and time to reach peak power output at different %1RM Through study completion, an average of 4 weeks Measuring during bench press and back squat exercises.
Number of repetitions performed in 1 set at 65%1RM until task failure Through study completion, an average of 4 weeks In bench press and back squat exercises
Bar velocity deplacement performed in 1 set at 65%1RM until task failure Through study completion, an average of 4 weeks In bench press and back squat exercises
Power output generated in 1 set at 65%1RM until task failure Through study completion, an average of 4 weeks In bench press and back squat exercise
Resting Metabolic Rate (RMR) Through study completion, an average of 4 weeks Kcal at rest measuring (RMR) using a metabolic chart.
Maximal Fat Oxidation Rate (MFO) Through study completion, an average of 4 weeks g/min (MFO) using a metabolic chart.
- Secondary Outcome Measures
Name Time Method Physical activity (METs-min/wk) Through study completion, an average of 4 weeks Using IPAQ
Dietary (g/kg of macronutrients) Through study completion, an average of 4 weeks Using 24-total recall
Mood state Through study completion, an average of 4 weeks Mood. Participants graded a set of 29 items related to the mood on a Likert scale from 0 (not at all) to 4 (extremely) in reply to the question;How do you feel at this moment?; to assess six scales: tension, depression, anger, vigor, fatigue and confusion.
Adverse effects Through study completion, an average of 4 weeks Adverse effects. perception of power, endurance, energy and exertion, as well as heart, muscular and gastrointestinal discomfort.
Fat mass Through study completion, an average of 4 weeks Using electrical bioimpedance (kg and % of body mass)
Fat-free mass Through study completion, an average of 4 weeks Using electrical bioimpedance (kg and % of body mass)
Trial Locations
- Locations (1)
Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá
🇪🇸Alcalá de Henares, Madrid, Spain