NCT06824805CompletedNot Applicable
Hypertension, Ethnicity and Exercise Trial
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- KU Leuven
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- office blood pressure at 30 minutes post exercise
Study Overview
Brief Summary
The main aim of this study is to investigate the acute effects of a single bout of isometric handgrip exercise (IHG) and a single bout of aerobic endurance exercise (AEX) on blood pressure, both immediately after exercise and during the subsequent activities of daily living in patients with high-normal to grade 1 hypertension of South-Asian or African descent living in Suriname.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •• Age 18 - 65 years
- •Patients with high- normal BP (SBP: 130 - 139 mmHg or and DBP: 85 - 89 mmHg) or stage I hypertension (SBP: 140 - 159 mmHg or DBP: 90 - 99 mmHg) according to the ESC/ESH guidelines [15]
- •Asian or African descent
- •Do not meet the level of physical activity recommended by the WHO based on self-report [15]
- •Non-medicated patients or patients using a maximum of 2 antihypertensive drugs
Exclusion Criteria
- •• Functional or mental limitation limiting the correct execution of an exercise bout
- •History of ischemic stroke, autonomic neuropathy, cardiovascular, renal, or pulmonary disease by self-report
- •Diabetes type I or II
- •Pregnancy
- •The presence of exercise induced signs of myocardial ischemia or complex ventricular arrhythmia during CPET
- •Patients using three or more antihypertensive drugs or patients with resistant hypertension
Arms & Interventions
control
No Intervention
seated control session
isometric handgrip exercise
Active Comparator
4x2 minutes of isometric handgrip exercise
Intervention: Exercise (Behavioral)
Aerobic exercise
Experimental
aerobic exercise at 40-60% HRres
Intervention: Exercise (Behavioral)
Outcomes
Primary Outcomes
office blood pressure at 30 minutes post exercise
Time Frame: 30 minutes postexercsie
office blood pressure at 30 minutes post exercise
Secondary Outcomes
- daytime blood pressure(mean of 8 hours after the intervention)
Investigators
Véronique Cornelissen
Professor
KU Leuven
Study Sites (1)
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