STUDY OF EFFECT OF NEPEFENAC ON SWELLING OF CENTRAL RETINA AFTER CATARACT SURGERY.

Not Applicable

Not yet recruiting

Conditions: Disorders of the eye following cataract surgery,

Registration Number: CTRI/2020/09/028097

Lead Sponsor: SANKARA EYE HOSPITAL SHIVAMOGGA

Brief Summary: Pseudophakic cystoid macular edema (PCME) is one of the common complication following catarct surgery with incidence asa high as 18%.

The emergence of OCT has provided a quick and non invasive means of diagnosis of PCME.

To prevent the production of prostaglandins and decrease the inflammatory effects, we routinely use NSAIDâ€™â€™s in the post operative period.

There are many studies , suggesting the effect of 0.1% nepafenac and 0.3% separately in the prevention of PCME.But there are no studies comparing 0.1% and 0.3 % nepafenac in the prevention of PCME.

Hence the purpose of my study is to compare the effect of 0.1% versus 0.3% nepafenac in the prevention of pseudophakic cystoid macular edema by measuring macular and choroidal thickness by means of OCT and assessing the visual outcome after cataract surgery in diabetic patients.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 66

Inclusion Criteria

Patients diagnosed with type 2 diabetes mellitus undergoing cataract surgery All patients of age ranging from 40 â€“ 70 years Patients with Uneventful cataract surgery with intraocular lens ( IOL) in bag Image quality > 40 Patients who are willing for follow up.

Exclusion Criteria

Patients diagnosed with Complicated cataract Mature cataract Uveitic cataract Macular edema at baseline Glaucoma associated with cataract Posterior capsular defect Intraocular lens in sulcus.
Patients on treatment for macular edema in the past 3 months.
Patients on anti -glaucoma drugs.
Cases with unusual post-op inflammation.
Other retinal pathologies requiring treatment / compromising vision.
Deviation from the specified technique of surgery.
Cases requiring YAG capsulotomy within the follow up period.
Patients not willing for follow up according to fixed schedule.
Cases who require laser photocoagulation in last 3 months.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effect of 0.1% versus 0.3% Nepafenac in changes in macular thickness after cataract surgery in diabetes patients.	preoperatively and postoperatively at 1 week,1 month and 3 months.

Secondary Outcome Measures

Name	Time	Method
To compare the effect of 0.1% versus 0.3% Nepafenac in changes in choroidal thickness after cataract surgery in diabetes patients	To compare the visual outcome following cataract surgery in diabetic patients.

Trial Locations

Locations (1): SANKARA EYE HOSPITAL
🇮🇳
Shimoga, KARNATAKA, India
SANKARA EYE HOSPITAL
🇮🇳Shimoga, KARNATAKA, India
DR DEEPIKA V
Principal investigator
9566097087
drdeepikarajesh9988@gmail.com