Adaptive Support Ventilation in the Weaning of COPD

Phase 4

Completed

• Conditions: Pulmonary Disease, Chronic Obstructive

• Registration Number: NCT00969605
• Lead Sponsor: Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital

Brief Summary

Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation. Weaning with ASV shows promising results mainly in post-cardiac surgery patients. The aim of this randomized controlled study was to test the hypothesis that weaning with ASV could reduce the weaning duration in patients with chronic obstructive pulmonary disease (COPD) when compared with PSV.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Primary Completion: 2008-05
• Study Completion: 2008-12
• Study First Submitted: 2009-08-31
• Study First Submitted QC: 2009-08-31
• Status Verified: 2009-09
• Study First Posted: 2009-09-01
• Last Update Submitted: 2010-05-26
• Last Update Posted: 2010-05-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

• Diagnosis of COPD
• On invasive mechanical ventilation for at least 24 hours because of hypoxemic and/or hypercapnic respiratory failure

Exclusion Criteria

• Mechanical ventilation less then 24 hours (self extubation or death),
• Having a tracheotomy and
• COPD coexisted with severe cardiac or neurologic diseases.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Weaning duration

Secondary Outcome Measures

Name	Time	Method
Weaning success
Length of stay in the ICU

Trial Locations

Locations (1)

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital, Intensive Care Unit; 🇹🇷 Izmir, Turkey