Adaptive Support Ventilation in the Weaning of COPD
Phase 4
Completed
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- Procedure: Comparison of two different modes for weaning from mechanical ventilation
- Registration Number
- NCT00969605
- Lead Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
- Brief Summary
Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation. Weaning with ASV shows promising results mainly in post-cardiac surgery patients. The aim of this randomized controlled study was to test the hypothesis that weaning with ASV could reduce the weaning duration in patients with chronic obstructive pulmonary disease (COPD) when compared with PSV.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 97
Inclusion Criteria
- Diagnosis of COPD
- On invasive mechanical ventilation for at least 24 hours because of hypoxemic and/or hypercapnic respiratory failure
Exclusion Criteria
- Mechanical ventilation less then 24 hours (self extubation or death),
- Having a tracheotomy and
- COPD coexisted with severe cardiac or neurologic diseases.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Pressure support ventilation Comparison of two different modes for weaning from mechanical ventilation - Adaptive support ventilation Comparison of two different modes for weaning from mechanical ventilation -
- Primary Outcome Measures
Name Time Method Weaning duration
- Secondary Outcome Measures
Name Time Method Weaning success Length of stay in the ICU
Trial Locations
- Locations (1)
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital, Intensive Care Unit
🇹🇷Izmir, Turkey