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Clinical Trials/NCT03267849
NCT03267849CompletedNot Applicable

Lamina Cribrosa Depth Change With Change in Eye Pressure

Johns Hopkins University2 sites in 1 country309 target enrollmentStarted: July 1, 2017Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
309
Locations
2
Primary Endpoint
Change in anterior lamina cribrosa depth
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Detailed Description

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Diagnostic
Masking
None

Eligibility Criteria

Ages
21 Years to 100 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •persons who consent to drink water and be imaged

Exclusion Criteria

  • •non-consenting persons
  • •those who cannot be imaged

Outcomes

Primary Outcomes

Change in anterior lamina cribrosa depth

Time Frame: Up to 2 months

OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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