Lamina Cribrosa Depth Change With Change in Eye Pressure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 309
- 试验地点
- 1
- 主要终点
- Change in anterior lamina cribrosa depth
研究概览
简要总结
This is a study of the compliance of the lamina cribrosa with change in eye pressure.
详细描述
Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •persons who consent to drink water and be imaged
排除标准
- •non-consenting persons
- •those who cannot be imaged
研究组 & 干预措施
persons drinking water
all persons in the study will have images of the eye at baseline eye pressure, then the intervention will be to drink 2 bottles of water to increase eye pressure or decrease eye pressure, then will have images taken a second time
干预措施: wearing swimming goggles or having laser suturelysis (Other)
结局指标
主要结局
Change in anterior lamina cribrosa depth
时间窗: Up to 2 months
OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure
次要结局
未报告次要终点