The effect of intraileal infusion of fat emulsions, differing in degree of saturation, on satiety and food intake after a liquid meal replacement

eiden University Medical Centre (LUMC) (Netherlands)0 个研究点目标入组 15 人开始时间: 2006年1月27日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Evidence of severe cardiovascular, respiratory, urogenital, gastrointestinal/ hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat), dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological/psychiatric diseases, allergy, major surgery and/or laboratory assessments which might limit participation in or completion of the study protocol
•2. Gastrointestinal or hepatic disorders influencing gastrointestinal absorption or transit
•3. The use of psychotropic drugs, including: benzodiazepines or alcohol in excess of 21 units/week for males and 14 units/week for females
•4. Concomitant medication that can increase gastric pH (e.g. antacids, protonpump-inhibitors, prostaglandins, anticholinergic agents, H2-receptor antagonists), or alter gastric emptying (e.g. metoclopramide, cisapride, domperidone and erythromycin, anticholinergics, tricyclic antidepressants, narcotic analgesics, adrenergic agents, calcium channel blockers), or alter intestinal transit (e.g. loperamide, chemical/osmotic/bulk laxatives), or influence satiety/energy intake (e.g. sibutramine, glucocorticoids, anabolic steroids)
•5. Intolerance of Slim Fast product or of ingredients of the ad libitum meal
•6. Pregnancy, lactation, wish to become pregnant during study, or having a positive pregnancy test at inclusion
•7. Reported unexplained weight loss/gain of more than 2 kg in the month before the study enrolment

发起方

eiden University Medical Centre (LUMC) (Netherlands)