Characterisation of Autonomic function in Atrial Fibrillation; AF-AF Study

Centre for Heart Rhythm Disorders, The University of Adelaide0 个研究点目标入组 500 人开始时间: 2019年2月8日最近更新: 2019年7月15日

适应症

试验速览

暂无简介。

•Patients with Atrial Fibrillation (any stage of treatment or type). Control patients - healthy patients without any significant disease, patients with risk factors for AF but without disease as well as patients with other conditions which cause a high heart rate (inappropriate sinus tachycardia, postural tachycardia syndrome or supraventricular tachycardia) as well those with these conditions treated with catheter ablation in an area of the heart different to AF will be studied to compare reflex responses.

•Hemodynamically relevant cardiac valvular disease, symptomatic coronary artery disease, peripheral artery disease
•Known autonomic disorder (including severe peripheral/autonomic neuropathy in diabetic patients).
•oDiabetes itself is not an exclusion
•Significant cognitive impairment
•Parkinson’s disease
•History of stroke
•Poor mobility – unable to enter LBNP chamber
•Unable to have anti-arrhythmic drugs (AAD) and antihypertensives withheld for 5-7 days pre-autonomic testing.

发起方

Centre for Heart Rhythm Disorders, The University of Adelaide