Effect of two doses of epidural steroid injection on body steroid levels

Phase 3

Completed

• Conditions: Health Condition 1: null- Chronic Low back pain with or without radicular pain

• Registration Number: CTRI/2014/12/005324
• Lead Sponsor: Department of Science Technology Chandigarh Administration

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Chronic low-back pain due to disc prolapse, lumbar spondylosis, and/or spinal stenosis, for at least 3 month refractory to conservative or interventional therapies with pain score of more than 5.

Exclusion Criteria

coagulopathy, infection at the procedure site, allergy to corticosteroids, pregnancy, all endocrinology diseases, history of corticosteroid treatment in the preceding year, desi medications, chronic medical illnesses (diabetes, hypertension, heart failure, renal disease, liver disease, etc.), taking contraceptives, severe stress in the preceding month, those working at night shifts and grossly obese patients. None of the subjects consumes alcohol 12 hours before sampling or food one hour before sampling.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma Cortisol and ACTH levelsTimepoint: one, two and four weeks

Secondary Outcome Measures

Name	Time	Method
1. Overall VAS <br/ ><br>2. Overall MODQ <br/ ><br>Timepoint: Baseline, 0.5, 1, 2 and 3 months