The ARISE Study - Use of Vertical Positioning

Not Applicable

Not yet recruiting

• Conditions: Acute Respiratory Distress Syndrome

• Registration Number: NCT07025421
• Lead Sponsor: University of Alabama at Birmingham

Brief Summary

The pilot study will randomize 40 ARDS patients who if proning were required would be randomized to upright bed positioning or to stand of care with bed in the head of bed elevation position

Detailed Description

Patients will be randomized to receive either daily upright bed positioning or to receive standard of care with head of bed elevated.

Study Timeline

• Status Verified: 2025-06
• Study First Submitted: 2025-06-09
• Study First Submitted QC: 2025-06-09
• Last Update Submitted: 2025-06-09
• Study First Posted: 2025-06-17
• Last Update Posted: 2025-06-17
• Study Start: 2025-07-01
• Primary Completion: 2026-06-30
• Study Completion: 2026-08-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Acute Respiratory Distress Syndrome

Exclusion Criteria

• Cancer
• Active tracheostomy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in Tidal Volume	within first 7 days of mechanical ventilation	Mechanical Ventilator Tidal Volume

Trial Locations

Locations (1)

University of Alabama at Birmingham; 🇺🇸 Birmingham, Alabama, United States