Decision Making in Degenerative Lumbar Spine : CT vs. MRI

• Conditions: Degenerative Lumbar Disease

• Registration Number: NCT04130035
• Lead Sponsor: Assiut University

Brief Summary

To identify the optimal imaging modality involved in decision making in patients with degenerative lumbar spine using CT vs. MRI.

Detailed Description

* There is 266 million individuals (3.63%) worldwide have DSD and LBP each year; the highest and lowest estimated incidences were found in Europe (5.7%) and Africa (2.4%), respectively. Based on population sizes, low- and middle-income countries have 4 times as many cases as high-income countries. Thirty-nine million individuals (0.53%) worldwide were found to have Spondylolisthesis, 403 million (5.5%) individuals worldwide with symptomatic disc degeneration, and 103 million (1.41%) individuals worldwide with spinal stenosis annually.

* Degenerative disease of the lumbar spine is a significant cause of disability in the world; it encompasses conditions such as Spondylolisthesis, disc degeneration, and lumbar spinal stenosis. Associated with a variety of clinical symptoms, including lower extremity pain, weakness, and low back pain (LBP) of varying levels of severity.

* Imaging plays an important role in the evaluation of degenerative spine.

* Plain films still play an important role in evaluation of the spine, because the examination is inexpensive and available and gives a wide panoramic view of the spine. Direct information about bony structures can be obtained, and functional information about misalignment and vertebral stability can be obtained with upright dynamic films in flexion-extension and lateral bending.

* Computerized axial tomography (CAT) scan: CT scan shows soft tissues such as ligaments and muscles more clearly than traditional X-rays do, so it is more useful for diagnosing certain problems, such as ruptured or degenerated discs and spinal stenosis.

* Magnetic resonance imaging (MRI): The advantage of MRI scans over X-rays and CT scans is that MRI provides clear, detailed images of the soft-tissue structures, such as the muscles, cartilage, ligaments, discs, tendons and blood vessels, in addition to the bones.

Study Timeline

• Status Verified: 2019-10
• Study First Submitted: 2019-10-15
• Study First Submitted QC: 2019-10-16
• Last Update Submitted: 2019-10-16
• Study First Posted: 2019-10-17
• Last Update Posted: 2019-10-17
• Study Start: 2019-11-01
• Primary Completion: 2021-11-01
• Study Completion: 2021-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• degenerative lumbar spine diseases.
• age more than 18.

Exclusion Criteria

• Patients with contraindications for MRI.
• Patients with spinal implants in the target region.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
comparison between CT vs. MRI in decision making in degenerative lumbar spine.	baseline	Differences in decision making in patients of lumbar degenerative spine based on CT vs. MRI.

Secondary Outcome Measures

Name	Time	Method
The correlation between the image finding and intraoperative finding.	baseline	The correlation between the image finding and intraoperative finding.