Managing the Nutritional Needs of Older Filipino with Due Attention to Protein Nutrition and Functional Health (ManoPo) Study
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Sarcopenia
- 发起方
- Food and Nutrition Research Institute, Philippines
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Change in muscle strength, as measured by grip strength and leg strength (Jamar, MicroFET)
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
The study aims to determine the effect of protein nutrition and exercise on the body composition and functional capacity of Filipino older adults.
详细描述
The objective of the study is to determine the effects of nutrition supplementation and exercise intervention on the main indicators of sarcopenia in older adults such as body composition (fat mass and lean mass), muscle strength (leg and handgrip), and physical performance.
研究者
Robby Carlo A. Tan
Senior Science Research Specialist
Food and Nutrition Research Institute, Philippines
入排标准
入选标准
- •Pre-sarcopenia/pre-frail
- •Aged 60 years old and above, male or female
- •Free-living in the community, ambulatory
- •Able to respond to food recall/interview as self-declared
- •Normal cardiac function as measured by resting ECG
排除标准
- •Bed ridden, unable to perform exercise independently
- •Presence of serious medical condition (i.e. cancer, existing fracture)
- •Presence of unmanaged hypertension and/or type 2 diabetes or upon assessment of physician
- •Renal Problem
- •Under controlled or medically-supervised diet not flexible to include the intervention agent
- •Allergic to any ingredients in the nutrition supplementation
结局指标
主要结局
Change in muscle strength, as measured by grip strength and leg strength (Jamar, MicroFET)
时间窗: Baseline, Midline (6 weeks), Endline (12 weeks)
Handgrip strength is measured using a hydraulic hand dynamometer through maximum exertion of grip force (in kilograms). Leg strength is measured using a hand-held dynamometer. Participant will use strongest leg force to push against the resistance brought upon by the researcher while holding the measuring device.
Change in physical performance, as measured by timed up-and-go test
时间窗: Baseline, Midline (6 weeks), Endline (12 weeks)
Faster time duration to complete the test indicate lesser risk for falls
Change in physical performance, as measured by short physical performance battery
时间窗: Baseline, Midline (6 weeks), Endline (12 weeks)
Score ranges from 0 to 12 with a higher score indicating better functionality
Change in physical performance, as measured by 10-meter walk test
时间窗: Baseline, Midline (6 weeks), Endline (12 weeks)
Faster walking speed (in meters per second) indicate better functionality
Change in muscle mass, as measured by dual-energy x-ray absorptiometry (DXA)
时间窗: Baseline, Midline (6 weeks), Endline (12 weeks)
Measurement of appendicular skeletal muscle mass index (ASMI) by dividing total muscle mass (kg) of appendages with height in meters squared