The Body's Response to Food Intake in Trained, Older Adults

Purdue University1 site in 1 country50 target enrollmentSeptember 2006

ConditionsElderly

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Elderly
Sponsor: Purdue University
Enrollment: 50
Locations: 1
Primary Endpoint: Quantify the acute effects of fluid and solid foods on post-prandial (post-meal) appetite and food intake at the next eating occasion in trained and untrained, elderly people.
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this research study is to determine the effects of food supplements and strength training on appetite, the amount of energy expended, and body composition.

Registry

clinicaltrials.gov

Start Date

September 2006

End Date

May 2008

Last Updated

12 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Purdue University

Responsible Party

Principal Investigator

Wayne Campbell

Professor, Foods and Nutrition

Purdue University

Eligibility Criteria

Inclusion Criteria

•All subjects must meet the following eligibility criteria:
•Age range: 60 years and older
•Body mass index between 20-29 kg/m2
•Weight stable (\< 2 kg weight change within last 6 months)
•Non-smoking
•Constant habitual activity patterns within last 3 months
•Clinically normal blood profiles (specifically, normal liver and kidney function; normal complete blood count (non-anemic); fasting blood glucose \<110 mg/dl)
•Not taking medications known to influence appetite or metabolism
•Non-diabetic
•Confirmation of acceptability of eating the study test foods (solids and fluids)

Exclusion Criteria

•All subjects will be excluded based on the following exclusionary criteria:
•Age: \<60 years
•Body mass index: outside of the 20-29 kg/m2 range
•Gained or lost \> 4.5 kg within the last 6 months
•Smoker (currently or within the last year)
•Intermittently been involved in a diet and/or exercise program within the last 3 months
•Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
•Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
•Abnormal heart function (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD
•Clinically diagnosed as diabetic

Outcomes

Primary Outcomes

Quantify the acute effects of fluid and solid foods on post-prandial (post-meal) appetite and food intake at the next eating occasion in trained and untrained, elderly people.

Time Frame: 6 weeks

Secondary Outcomes

Quantify the contribution of selected satiety factors (glucose, insulin, CCK, ghrelin, and GLP-1) and gastrointestinal transit time, to the differential appetitive responses to fluid versus solid foods in trained and untrained, elderly people(6 weeks)