Dextromethorphan in smoking related cough

Completed

• Conditions: Respiratory: Smoking related cough; Respiratory; Smoking related cough

• Registration Number: ISRCTN46985377
• Lead Sponsor: Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09-12
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

50 volunteers between 18 - 70 years.

Exclusion Criteria

Not provided at time of registration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in cough frequency measured subjectively after waking on treatment day 1 over time periods 0 - 10, 10 - 20, 20 - 40 and 40 - 60 minutes.

Secondary Outcome Measures

Name	Time	Method
1. Reduction in cough frequency on days 2 - 5<br>2. Change in cough symptoms (severity expectoration, chest pain, etc.,) and nocturnal cough<br>3. Change in cough threshold as measured via citric acid cough challenge