Effectiveness of Intravenous Tranexamic Acid in Reducing Blood Loss During and After Cesarean Section
- Registration Number
- NCT02279186
- Lead Sponsor
- Ain Shams Maternity Hospital
- Brief Summary
In this study, the efficacy and safety of tranexamic acid in the reducing the blood loss during and after elective LSCS will be investigated.
- Detailed Description
To state the effectiveness clinically and laboratory and safety of tranexamic acid in reducing blood loss during and after the elective lower segment cesarean section.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 200
Inclusion Criteria
-
- Women undergoing caesarean delivery for various elective indications.
- Full term primiparas / multiparas.
- Singleton pregnancy being delivered by LSCS.
Exclusion Criteria
-
- Medical problems involving the heart, liver, kidney and brain .
- Blood disorders.
- Allergy to tranexamic acid.
- History of thromboembolic disorders, abnormal placentation, severe pre-eclampsia, uterine anomalies and pathology.
- Multiple pregnancy, macrosomia.
- Polyhydromnios .
- Patients requiring blood transfusion due to anemia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group A Tranexamic Acid receiving tranexamic acid
- Primary Outcome Measures
Name Time Method Amount of blood loss during cesarean section after placental delivery till end of the operation. during and 2hours post cesarean section
- Secondary Outcome Measures
Name Time Method 1.Vital signs eg:blood pressure ,heart rate ,respiratory rate during first two post operative hours . up to 24hours postoperative composite
Adverse affect of tranexamic acid on mother and neonate . first 24 hours eg:drug allergy ,drug interaction ,thrombotic manifestation and the number of participant .
24 hours post operative haemoglobin and haematocrit . after 24 hours. composite
Trial Locations
- Locations (1)
Ain Shams Maternity Hospital
🇪🇬Cairo, Egypt