MedPath

Effects of Curcumin on Diabetic Foot Treatment

Phase 2
Conditions
Diabetic Foot.
Diabetes mellitus due to underlying condition with foot ulcer
E08.621
Registration Number
IRCT20210413050958N4
Lead Sponsor
Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
35
Inclusion Criteria

Signed informed consent form
Patients with diabetic foot ulcer grade 3 and 4 according to the Wagner classification do not require surgery at this stage of wound healing.
Patients with ischemic foot ulcer are not included in the study.
Patients with pressure sore are not included in the study.
If the patient has renal failure undergoing dialysis, he/she will not be included in the study.

Exclusion Criteria

Not referring the patient for subsequent follow-ups so that the nurse can not dress the wound (travel or change the patient's place of residence)
Occurrence of any medical problem or surgery not related to wound healing that makes it impossible to continue the study (such as myocardial infarction or stroke, acute limb ischemia, sepsis for any reason other than the patient's wound and etc).
Hepatic failure
Biliary obstruction

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Wound healing (wound healing by epithelialization). Timepoint: The depth of the wound will be evaluated before and 100 days after the intervention. Method of measurement: Wound depth is measured using the vernier caliper at the maximum vertical diameter of the wound and wound healing will be determined according to the Wagner criterion.
Secondary Outcome Measures
NameTimeMethod
Fasting Blood Glucose. Timepoint: Before and 100 days after the intervention. Method of measurement: Laboratory kit.;HbA1c. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit.;Insulin. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit.;Lipid Profile. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit.
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