Motivational Interviewing and Guided Opioid Tapering Support to Promote Postoperative Opioid Cessation

Not Applicable

• Conditions: Opioid Cessation
• Interventions: Behavioral: Motivational Interviewing and Guided Opioid Tapering Support; Behavioral: Enhanced Usual Care

• Registration Number: NCT03659734
• Lead Sponsor: Stanford University

Brief Summary

The purpose of this study is to evaluate the relative efficacy of enhanced usual care versus motivational interviewing and guided opioid tapering support to promote opioid cessation after total hip or knee replacement surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-04-10
• Study First Submitted QC: 2018-09-04
• Study First Posted: 2018-09-06
• Study Start: 2019-07-12
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-16
• Last Update Posted: 2023-12-19
• Primary Completion: 2024-03
• Study Completion: 2024-06

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

• Planning to undergo surgery
• English speaking
• Ability and willingness to complete questionnaires and assessments
• Scheduled for total hip, knee, or shoulder replacement
• Preoperative opioid use and opioid use 14 days after surgery to increase the likelihood of delayed opioid cessation.
• Not under the care of a current pain management provider

Read More

Exclusion Criteria

• Any conditions causing inability to complete assessments
• Known pregnancy
• Elevated suicidality
• Enrollment in conflicting perioperative trial

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Motivational Interviewing and Guided Opioid Tapering Support	Motivational Interviewing and Guided Opioid Tapering Support	-
Enhanced Usual Care	Enhanced Usual Care	-

Primary Outcome Measures

Name	Time	Method
Time to Opioid Cessation	Through study completion, an average of 1 year	Time to opioid cessation between the two groups will be analyzed using survival analysis

Secondary Outcome Measures

Name	Time	Method
Opioid Misuse	Through study completion, an average of 1 year	Participant score on the Current Opioid Misuse Measure and prescription information obtained via CURES 2.0 will be used to assess opioid misuse behaviors.

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Palo Alto, California, United States