Comparative study of outcomes with adjunct use of disease modifying agents in management of knee osteoarthritis

Institute of Medical Sciences Banaras Hindu University Varanasi Uttar Pradesh India0 个研究点目标入组 217 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Inclusion Criteria:
•The patients with radiographic evidence of suffering grade I, II and grade III Osteoarthritis.
•The patients having mild to moderate grade of hypertension controlled with therapies as well as those with diabetes well controlled with therapies and suffering from osteoarthritis were also included.

•1.Patients suffering from severe grades of hypertension and diabetes mellitus requiring more than oral hypoglycemic therapies were excluded.
•2.Untreated or poorly controlled diabetics and hypertensives were excluded.
•3.Patients suffering from any other major systemic disease or active infection were excluded.
•4.Patients with H/O trauma to knee in past before or after the onset of osteoarthritic symptoms were excluded.
•5.Patients with more advanced (radiological grade IV) OA were excluded.
•6.Patients developing any illness causing restriction of routine for one day or more as also those needing more than 3 days course of therapy for emergent illness were excluded.
•7.Occasional use of single or two doses of medications up-to two instances during the 12 weeks observational period were allowed.
•8.No case of pregnancy or H/O any surgery in last 3 years was included.
•9.Patients non-compliant to therapy at more than two recalled occasions during any 2 weeks in treatment course were excluded.

发起方

Institute of Medical Sciences Banaras Hindu University Varanasi Uttar Pradesh India