Comparision of various drugs used inknee osteoarthritis
- Conditions
- Health Condition 1: null- Known as well as newly diagnosed cases of primary knee osteoarthritis
- Registration Number
- CTRI/2016/02/006587
- Lead Sponsor
- Institute of Medical Sciences Banaras Hindu University Varanasi Uttar Pradesh India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 217
Inclusion Criteria:
The patients with radiographic evidence of suffering grade I, II and grade III Osteoarthritis.
The patients having mild to moderate grade of hypertension controlled with therapies as well as those with diabetes well controlled with therapies and suffering from osteoarthritis were also included.
1.Patients suffering from severe grades of hypertension and diabetes mellitus requiring more than oral hypoglycemic therapies were excluded.
2.Untreated or poorly controlled diabetics and hypertensives were excluded.
3.Patients suffering from any other major systemic disease or active infection were excluded.
4.Patients with H/O trauma to knee in past before or after the onset of osteoarthritic symptoms were excluded.
5.Patients with more advanced (radiological grade IV) OA were excluded.
6.Patients developing any illness causing restriction of routine for one day or more as also those needing more than 3 days course of therapy for emergent illness were excluded.
7.Occasional use of single or two doses of medications up-to two instances during the 12 weeks observational period were allowed.
8.No case of pregnancy or H/O any surgery in last 3 years was included.
9.Patients non-compliant to therapy at more than two recalled occasions during any 2 weeks in treatment course were excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee injury and osteoarthritis outcome score (KOOS score)Timepoint: At first visit and at the end of 3 months
- Secondary Outcome Measures
Name Time Method nilTimepoint: nil