Treating Late-Life Generalized Anxiety Disorder (GAD) in Primary Care
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Generalized Anxiety Disorder
- Sponsor
- Baylor College of Medicine
- Enrollment
- 148
- Locations
- 1
- Primary Endpoint
- Anxiety
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The purpose of this study is to determine whether cognitive behavior therapy (CBT) is effective in the treatment of generalized anxiety disorder (GAD) in adults age 60 and older in a primary care setting.
Detailed Description
Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders among older adults. Anxiety in older adults is associated with decreased physical activity, poorer self-perceptions of health, decreased life satisfaction, and increased loneliness. Because many older adults with anxiety seek assistance in a medical setting, treatment has been primarily pharmacological. There is, however, limited evidence of the effectiveness of psychotropic medications. Given the potential difficulties in prescribing psychotropic medications in later life (e.g., increased adverse effects, potential drug interactions), psychosocial treatments may be important alternative or adjuncts. The treatment phase of this study lasts 10 weeks, during which patients will be randomly assigned to either cognitive behavior therapy (CBT) or usual care. Follow-up will last 12 months after treatment completion, during which time patients will complete telephone assessments.
Investigators
Melinda Stanley
Professor
Baylor College of Medicine
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of Generalized Anxiety Disorder
Exclusion Criteria
- •Active suicidal intent
- •Current psychosis
- •Current bipolar disorder
- •Substance abuse within past month
- •Cognitive impairment
Outcomes
Primary Outcomes
Anxiety
Time Frame: Baseline and 3, 6, 9, 12 and 15 months
Secondary Outcomes
- Satisfaction with CBT and general health care(Baseline and 3, 6, 9, 12 and 15 months)
- Depression(Baseline and 3, 6, 9, 12 and 15 months)
- Quality of life inventory (QOLI)(Baseline and 3, 6, 9, 12 and 15 months)
- Sleep quality(Baseline and 3, 6, 9, 12 and 15 months)
- Use of alcohol and other substances(Baseline and 3, 6, 9, 12 and 15 months)
- Functional and health status(Baseline and 3, 6, 9, 12 and 15 months)
- Service utilization(Baseline and 3, 6, 9, 12 and 15 months)