临床试验/NCT07508202

NCT07508202已完成4 期

Comparison of Mean Duration of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving US Transversus Abdominis Plane Block (TAP) With Bupivacaine and Dexmetomidine vs Bupivacaine nd Dexmethasone

Pakistan Institute of Medical Sciences1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2026年3月27日最近更新: 2026年7月14日

适应症

干预措施

试验速览

阶段: 4 期
状态: 已完成
发起方: Pakistan Institute of Medical Sciences
入组人数: 60
试验地点: 1
主要终点: Resuce analgesia

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding drugs to local anesthetic regimen

详细描述

TAPP block can provide significant post operative analgesia following lower abdominal surgery and its duration can be prolonged by adding adjuvants to local anesthetics.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Single (Participant)

入排标准

年龄范围: 18 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•ASA I and ASA II BMI 25-35 kg/m2 Lower abdominal surgeries below L2-L3 leves

排除标准

•Infection at block site Coagulopathy Antiplatelet

研究组 & 干预措施

Dexmedetomidine

Active Comparator

干预措施: Dexmedetomidine (Drug)

Dexamethasone

Active Comparator

干预措施: Dexamethasone (Drug)

结局指标

主要结局

Resuce analgesia

时间窗: Time in the post operative period when patient first demands rescues analgesia will be noted in minutes

次要结局

未报告次要终点

研究者

发起方

Pakistan Institute of Medical Sciences

申办方类型

Other Gov

责任方

Principal Investigator

主要研究者

Department of Anesthesia

Principal Investigator

Pakistan Institute of Medical Sciences

研究点 (1)

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