Respiratory Muscle Training in Ventilator Dependent Patients
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- ventilator dependent status
研究概览
简要总结
The purpose of this study is to determine if inspiratory muscle strength training will increase the proportion of ventilator dependent patients weaned versus Sham treated patients.
详细描述
The inspiratory muscle strength training consists of 4 sets of 6-10 breaths through a threshold inspiratory muscle strength training device, 5 days per week. The inspiratory muscle training is conducted at the highest pressure setting tolerated by the patients. The Sham groups uses an inspiratory muscle trainer that does not increase inspiratory muscle strength. Both the treated and Sham groups participate in progressively lengthening periods of breathing without ventilator as tolerated. Patients are considered weaned when they can breathe for 72 consecutive hours without any ventilator support.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Failure to wean patients in the medial, surgical and intermediate respiratory care units at Shands Hospital
- •medically stable
- •able to initiate spontaneous breaths
- •able to provide informed consent
- •able to follow simple instructions
排除标准
- •life expectancy < 12 months due to malignancy
- •damaged phrenic nerves
- •neuromuscular diseases
- •heart or lung transplant
结局指标
主要结局
ventilator dependent status
次要结局
- breathing patterns during failed and passed unsupported breathing trials
- maximal inspiratory pressure