Inspiratory Muscle Training in Ventilator Dependent Patients
- Conditions
- Failure to WeanRespiratory FailureVentilator Dependent
- Registration Number
- NCT00419458
- Lead Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Brief Summary
The purpose of this study is to determine if inspiratory muscle strength training will increase the proportion of ventilator dependent patients weaned versus Sham treated patients.
- Detailed Description
The inspiratory muscle strength training consists of 4 sets of 6-10 breaths through a threshold inspiratory muscle strength training device, 5 days per week. The inspiratory muscle training is conducted at the highest pressure setting tolerated by the patients. The Sham groups uses an inspiratory muscle trainer that does not increase inspiratory muscle strength. Both the treated and Sham groups participate in progressively lengthening periods of breathing without ventilator as tolerated. Patients are considered weaned when they can breathe for 72 consecutive hours without any ventilator support.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- Failure to wean patients in the medial, surgical and intermediate respiratory care units at Shands Hospital
- medically stable
- able to initiate spontaneous breaths
- able to provide informed consent
- able to follow simple instructions
- life expectancy < 12 months due to malignancy
- damaged phrenic nerves
- neuromuscular diseases
- heart or lung transplant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method ventilator dependent status
- Secondary Outcome Measures
Name Time Method breathing patterns during failed and passed unsupported breathing trials maximal inspiratory pressure
Trial Locations
- Locations (1)
Deprtment of Physical Therapy/Shands Hospital at the University of Florida
🇺🇸Gainesville, Florida, United States