The Effect of Cyclosporine on Head Trauma
Phase 2
- Conditions
- Diffuse Axonal Injury.Diffuse Brain Injury
- Registration Number
- IRCT2013011712164N1
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Inclusion criteria are:
Age between 16 and 75 years; GCS score less than 10 in 24 hours of admission; Complete consent form; ßHCG is negative and no pregnant patients.
Exclusion criteria are:
Negative brain stem reflex response; Patients with immune deficiency; Liver and kidney diseases; Penetrative brain injury; Multiple trauma; Past medical history of cancer; And patients that need emergency surgery; Pregnant women
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of Consciousness. Timepoint: 1day, 3month, 6month. Method of measurement: GCS, GOS-E, MMSE.
- Secondary Outcome Measures
Name Time Method iver Function Tests. Timepoint: 12hour, 24hour, 36hour, 48hour, 4day, 7day, 3month, 6month. Method of measurement: AST(Aspartat Aminotransferase), ALT(Alanine Aminotransferase), ALP(Alkaline Phosphatase).