A Comparative Clinical Study to Evaluate the Efficacy and Safety of Emotion to Emotion Therapy Versus VR-based Emotion-Emotion Thearpy for Treatment of Hwa-byung

Not Applicable

Recruiting

Conditions: Codes for special purposes

Registration Number: KCT0007871

Lead Sponsor: Daejeon Korean Medicine Hospital of Daejeon University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 96

Inclusion Criteria

1) Aged 19 to 79
2) Clincally diagnosed with Hwa-byung through a Hwa-byung Diagnostic Interview Schedule (HBDIS)
3) Participants who voluntarily decided to participate and signed the consent form

Exclusion Criteria

1) Participants at risk of suicide (Question no.9 on the BDI has more than 2 points, or with specific suicide thinking or suicide plans)
2) Participants with a history of severe psychiatric disorders (Severe psychiatric disorders refer to psychosis such as hallucinations and delusions. It is decided by a specialist of neuropsychiatry of Korean medicine or a resident of neuropsychiatry of Korean medicine.)
3) Participants who have been treated by Korean medicine to Hwa-byung in recent 4 weeks.
4) Seriously unstable medical conditions (It is decided based on lab tests, vital signs, and etc. by investigator.)
5) Hyperthyrodism or Hypothyrodism (over 2 times the upper reference limit of TSH and Free T4 or below 0.75 times the lower reference limit of TSH and Free T4, or taking medication for hyperthyrodism or hypothyroidism
6) Participants who are thought to be not appropriate to participate in this trial by the investigator.

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ikert Scale for Major Symptoms of Hwa-byung Symptoms (HB-M)

Secondary Outcome Measures

Name	Time	Method
ikert Scale for Major Symptoms of Hwa-byung Symptoms (HB-M);The Core Seven-Emotions Inventory Short From (CSEI-S);Patient Health Questionnaire-15 (PHQ-15);Stress Response Index (SRI);Beck Depression Inventory (BDI);State-Trait Anger Expression Inventory (STAXI);State-Trait Anxiety Inventory (STAI);Insomnia Severity Index;Functional Near-infrared Spectroscopy (fNIRS);Heart Rate Variability (HRV)