Impact of Infectious Diseases Consultation on Vaccination Coverage Among People Waiting for a Kidney Transplant at the Clermont-Ferrand Hospital
- Conditions
- Kidney Transplantation
- Interventions
- Other: Specific infectious diseases consultation
- Registration Number
- NCT04791098
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Brief Summary
Solid-organ transplant patients are at increased risk of infectious diseases. Among this population, infectious diseases may be life-threatening or lead to graft rejection. Their prevention is an important challenge. Despite specific national recommendations, vaccination is underutilized. That is why we propose a dedicated infectious diseases consultation during pre-kidney transplantation assessment.
- Detailed Description
The main objective of this study is to impove vaccine coverage before kidney transplantation.
Enrollment was based on the waiting list for a kidney transplant. Patients newly listed are invited to participate by the transplant team (nephrology department) ; for those that are already registered, a notification letter is sent to their home.
All patients included must :
* complete a health questionnaire
* take a blood test at day 0 : viral, bacterial and parasitic serologies, QuantiFERON-TB
* take a chest X-ray and dental panoramic Patients randomized in interventional group will be seen in specific infectious diseases consultation at Clermont Ferrand Hospital. A letter of recommendations is sent to nephrologist for patients randomized in group control.
The primary study endpoint (immunization coverage) is evaluated at 6 months.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 150
- Patient over 18
- On the waiting list for kidney transplantation at Clermont-Ferrand
- Free and informed consent
- Affiliation to a social security system
- Patient under 18
- Protected adults (individuals under guardianship by court order
- Pregnant and nursing women
- Prior graft (solid organs or hematopoietic stem cells)
- Absence of consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Stronger pre-transplant check-up Specific infectious diseases consultation routine patient management + specific infectious diseases consultation
- Primary Outcome Measures
Name Time Method Vaccination coverage Month 6 The percentage of fully immunized patients according to the Recommendations of High Council for public Health
- Secondary Outcome Measures
Name Time Method Mortality Month 6 Mortality after kidney transplantation
Infectious complications within the 6 months of the transplantation Infectious diseases which require special management (hospitalization, anti-infective treatments)
Trial Locations
- Locations (1)
CHU de Clermont-Ferrand
🇫🇷Clermont-Ferrand, France