Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 233
- 试验地点
- 1
- 主要终点
- Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
研究概览
简要总结
COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our aim is to further explore the relationship between COVID-19 and tinnitus. For this purpose we analyzed people in the city of Volta Redonda, Brazil after a COVID-19 infection. In detail we compared those with new onset tinnitus during or after COVID-19 with those without tinnitus and those with tinnitus onset before the COVID-19 infection. Moreover we analyzed the prevalence of post-COVID tinnitus along the pandemic timeline, from 2020 to 2024.
详细描述
Two-hundred and thirty three patients over 18 years old and previously diagnosed with COVID-19 confirmed by either a RT-PCR, antibodies or antigens test were included. Patients were subdivided in three groups: no tinnitus (NT), tinnitus that already existed before COVID-19 (chronic tinnitus, CT) and tinnitus that arose during or after COVID-19 (post-COVID-19 tinnitus, PCT). Data concerning COVID-19 symptoms, drugs prescribed for COVID-19, tinnitus characteristics, comorbidities and other otological symptoms were collected. Tinnitus assessment included pure tone audiograms, the Tinnitus Handicap Inventory (THI), visual-analog scales (VAS) for loudness and distress as well as the hospital anxiety and depression scale (HADS). Patients with CT were additionally asked whether their tinnitus worsened after their COVID-19 infection.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •previous COVID-19 infection
排除标准
- •not willing to give informed consent
结局指标
主要结局
Trajectory of COVID-Related Tinnitus Over the Pandemic Timeline
时间窗: February 2023 - November 2024
Post-COVID tinnitus x No tinnitus x chronic tinnitus
次要结局
未报告次要终点
研究者
Ricardo Rodrigues Figueiredo
MD,MSc,PhD
Faculdade de Medicina de Valenca