MedPath

Neurovascular Product Surveillance Registry

Recruiting
Conditions
Intracranial Aneurysm
Stroke, Ischemic
Interventions
Device: Treatment for intracranial aneurysms
Device: Treatment for Acute Ischemic Stroke
Registration Number
NCT02988128
Lead Sponsor
Medtronic Neurovascular Clinical Affairs
Brief Summary

Post market surveillance registry

Detailed Description

An observational, prospective, multi-center, single-arm registry to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic Neurovascular market-released products used in the treatment of Intracranial aneurysms and Acute Ischemic Stroke.

MDT16056 and MDT17077 are conducted under the Product Surveillance Registry (NCT01524276).

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
4000
Inclusion Criteria
  • Patient or legally authorized representative (LAR) provides authorization and/or consent per institution and geographical requirements
  • Patient has, or is intended to receive or be treated with, an eligible Medtronic product
  • Patient is consented within the enrollment window of the therapy received, as applicable
  • Patient is at least 18 years of age at time of enrollment.
Exclusion Criteria
  • Patient who is, or is expected to be inaccessible for follow-up
  • Patient with exclusion criteria required by local law
  • Patient is currently enrolled in or plans to enroll in any concurrent drug and/or device study that may confound results
  • Female patient who is known to be pregnant or is breastfeeding or wishes to become pregnant during participation in the study.

For MDT24028 and MDT22032:

General Inclusion Criteria:

  • Patient or legally authorized representative (LAR) provides authorization and/or consent per institution and geographical requirements.
  • Patient is treated or intended to be treated with an eligible Medtronic Neurovascular product.
  • Patient is an adult per local law at time of consent. Medtronic Business Restricted This document is electronically controlled CONFIDENTIAL 056-F275 Rev F Clinical Investigation Plan Template

General Exclusion Criteria:

  • Patient who may be unable to complete the study follow-up
  • Patient with any contraindications per the applicable Instructions for Use document
  • Female patient who is known to be pregnant or is breastfeeding or wishes to become pregnant during participation in the study
  • Patient is currently enrolled in, or plans to enroll in, any concurrent drug/device study that may confound the study results.

Additional criteria may be required, refer to cohort-specific Addendum, as applicable, for further guidance.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Intracranial aneurysmTreatment for intracranial aneurysmsPatients undergoing treatment for intracranial aneurysms (IA) with Medtronic market approved device(s).
Acute Ischemic StrokeTreatment for Acute Ischemic StrokePatients undergoing treatment for acute ischemic stroke (AIS) with Medtronic market approved device(s).
Primary Outcome Measures
NameTimeMethod
Functional Independence: mRS score ≤ 290 days

For Acute ischemic stroke the primary outcome is functional Independence: modified Rankin Scale (mRS) score ≤ 2

The clinical success rate defined as complete occlusion of target aneurysm without retreatment or significant artery stenosis (≤ 50%).1 year

For Intracranial Aneurysm the primary outcome is the clinical success rate defined as complete occlusion of target aneurysm without retreatment or significant artery stenosis (≤ 50%).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (98)

ENERI

🇦🇷

Buenos Aires, Argentina

Klinikum Augsburg

🇩🇪

Augsburg, Germany

Qujing First Peoples Hospital

🇨🇳

Qujing, China

Centre Hospitalier Bretagne Atlantique Vannes - Auray

🇫🇷

Vannes, France

Hospital Universitario de La Paz

🇪🇸

Madrid, Spain

Gold Coast University Hospital

🇦🇺

Southport, Australia

Universitätsklinikum Christian Doppler Klinik Salzburg

🇦🇹

Salzburg, Austria

Ziekenhuis Oost Limburg - Campus Sint-Jan

🇧🇪

Genk, Belgium

Universitair Ziekenhuis Gent

🇧🇪

Gent, Belgium

Xuanwu Hospital Capital Medical University

🇨🇳

Beijing, China

Chongqing University Three Gorges Hospital

🇨🇳

Chongqing, China

The Affiliated Hospital of Jinggangshan University

🇨🇳

Ji'an, China

First Affiliated Hospital of Jiamusi University

🇨🇳

Jiamusi, China

Kaifeng Central Hospital

🇨🇳

Kaifeng, China

Liaocheng People's Hospital

🇨🇳

Liaocheng, China

Lishui Municipal Central Hospital

🇨🇳

Lishui, China

The Second Affiliated Hospital of Nanchang University

🇨🇳

Nanchang, China

The Second Nanning Peoples Hospital

🇨🇳

Nanning, China

Panzhihua Central Hospital

🇨🇳

Panzhihua, China

Yangpu District Central Hospital Shanghai Yangpu Hospital Tongji University

🇨🇳

Shanghai, China

Shanxi Cardiovascular Hospital

🇨🇳

Taiyuan, China

The First Affiliated Hospital Of Xi'an Jiaotong University

🇨🇳

Xi'an, China

The First Peoples Hospital of Xianyang

🇨🇳

Xianyang, China

Zhangzhou Municipal Hospital of Fujian Province

🇨🇳

Zhangzhou, China

Zhuhai Peoples Hospital

🇨🇳

Zhuhai, China

Zhumadian Central Hospital

🇨🇳

Zhumadian, China

Rigshospitalet

🇩🇰

Copenhagen, Denmark

Turun Yliopistollinen keskussairaala

🇫🇮

Turku, Finland

CHU Besancon - Hôpital Jean Minjoz

🇫🇷

Besançon, France

CHU de Bordeaux - Centre Universitaire Pellegrin

🇫🇷

Bordeaux, France

CHU Brest, Hôpital de la Cavale Blanche

🇫🇷

Brest, France

Hôpital Pierre Wertheimer

🇫🇷

Bron, France

CHU de Caen

🇫🇷

Caen, France

Centre Hospitalier Universitaire de Clermont-Ferrand - Gabriel-Montpied

🇫🇷

Clermont-Ferrand, France

CHU Dijon Bourgogne

🇫🇷

Dijon, France

AP-HP Hôpital Bicêtre

🇫🇷

Le Kremlin-Bicêtre, France

CHU Limoges - Hôpital Dupuytren

🇫🇷

Limoges, France

Hôpital de la Timone-CHU de Marseille

🇫🇷

Marseille, France

CHU de Montpellier - Hôpital Gui de Chauliac

🇫🇷

Montpellier, France

CHU de Nancy - Hôpital Central

🇫🇷

Nancy, France

CHU de Nantes Hôpital Laennec

🇫🇷

Nantes, France

GHU Paris Psychiatrie & Neurosciences

🇫🇷

Paris, France

Fondation Ophtalmologique Adolphe de Rothschild

🇫🇷

Paris, France

Hôpital de la Pitié Salpétrière

🇫🇷

Paris, France

CHU Reims Hôpital Maison Blanche

🇫🇷

Reims, France

CHU Hôpitaux de Rouen - Hôpital Charles Nicolle

🇫🇷

Rouen, France

CHU Toulouse - Hôpital Pierre-Paul Riquet

🇫🇷

Toulouse, France

CHRU de Tours - Hôpital Brettoneau

🇫🇷

Tours, France

Charité Universitätsmedizin Berlin -Campus Charite

🇩🇪

Berlin, Germany

Knappschaftskrankenhaus Bochum-Langendreer - Universitätsklinik

🇩🇪

Bochum, Germany

HELIOS Klinikum Erfurt

🇩🇪

Erfurt, Germany

Universitätsklinikum Erlangen

🇩🇪

Erlangen, Germany

Alfried Krupp Krankenhaus

🇩🇪

Essen, Germany

Universitätsklinikum Freiburg

🇩🇪

Freiburg, Germany

Universitätsklinikum Hamburg-Eppendorf

🇩🇪

Hamburg, Germany

Universitätsklinikum Heidelberg

🇩🇪

Heidelberg, Germany

LMU Klinikum der Universität München

🇩🇪

Munich, Germany

Klinikum Nürnberg - Klinikum Nürnberg Süd

🇩🇪

Nürnberg, Germany

Hellenic Airforce 251 General Hospital

🇬🇷

Athen, Greece

Prince of Wales Hospital

🇭🇰

Hong Kong, Hong Kong

The University of Hong Kong

🇭🇰

Hong Kong, Hong Kong

Országos Klinikai Idegtudományi Intézet

🇭🇺

Budapest, Hungary

Hadassah Medical Organization

🇮🇱

Jerusalem, Israel

Sheba Medical Center

🇮🇱

Ramat Gan, Israel

Azienda Ospedaliero-Universitaria Careggi

🇮🇹

Firenze, Italy

Azienda Ospedaliera Ospedale Niguarda Cà Granda

🇮🇹

Milano, Italy

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

🇮🇹

Milan, Italy

Chungnam National University Hospital

🇰🇷

Daejeon, Korea, Republic of

Chonnam National University Hospital

🇰🇷

Gwangju, Korea, Republic of

Chosun University Hospital

🇰🇷

Gwangju, Korea, Republic of

Jeonbuk National University Hospital

🇰🇷

Jeonju, Korea, Republic of

Severance Hospital

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Center

🇰🇷

Seoul, Korea, Republic of

Asan Medical Center

🇰🇷

Seoul, Korea, Republic of

Ajou University Medical Center

🇰🇷

Suwon, Korea, Republic of

Ulsan University Hospital

🇰🇷

Ulsan, Korea, Republic of

Military Medical Institute-Wojskowy Instytut Medyczny

🇵🇱

Warszawa, Poland

Centro Hospitalar de Vila Nova de Gaia/Espinho - Unidade I

🇵🇹

Vila Nova de Gaia, Portugal

Siberian Federal Biomedical Research Center

🇷🇺

Novosibirsk, Russian Federation

Almazov National Medical Research Centre

🇷🇺

St. Petersburg, Russian Federation

CINRE s.r.o.

🇸🇰

Bratislava, Slovakia

Chris Hani Baragwaneth Hospital

🇿🇦

Johannesburg, South Africa

Hospital De Cruces

🇪🇸

Barakaldo, Spain

Hospital Vall D'Hebron

🇪🇸

Barcelona, Spain

Hospital Fundación Jiménez Díaz

🇪🇸

Madrid, Spain

Hospital Universitario Central de Asturias

🇪🇸

Oviedo, Spain

Hospital Universitario Donostia

🇪🇸

San Sebastián, Spain

Hospital Universitario Virgen del Rocío

🇪🇸

Sevilla, Spain

Hospital Clínico Universitario de Valladolid

🇪🇸

Valladolid, Spain

Hospital Álvaro Cunqueiro

🇪🇸

Vigo, Spain

Universitätsspital Basel

🇨🇭

Basel, Switzerland

Inselspital - Universitätsspital Bern

🇨🇭

Bern, Switzerland

Hôpitaux Universitaires de Genève

🇨🇭

Geneve, Switzerland

Cleveland Clinic - Abu Dhabi

🇦🇪

Abu Dhabi, United Arab Emirates

University Hospitals of Birmingham NHS Foundation Trust - Queen Elizabeth Hospital

🇬🇧

Birmingham, United Kingdom

Imperial College Healthcare NHS Trust - Charing Cross Hospital

🇬🇧

London, United Kingdom

Barking, Havering and Redbridge University Hospitals - Queen's Hospital

🇬🇧

Romford, United Kingdom

University Hospitals of North Midlands NHS Trust - Royal Stoke University Hospital

🇬🇧

Stoke on Trent, United Kingdom

© Copyright 2025. All Rights Reserved by MedPath