NL-OMON50438
Recruiting
Not Applicable
Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age - 90+ Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alzheimer's disease
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 114
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \>\= 90 years (for the subjects with cognitive impairment an exception will be
- •made; also subjects between 85 and 90 years will be included)
- •Candidate is able to walk 400 meter independently (with or without walking aid)
- •No significant visual or hearing impairment (as judged by clinician),
- •Cognitively intact group:
- •\- MMSE \>\= 27 points, , this inclusion criteria is not applicable to the subjects
- •\>\= 100 years old (as a consequence of their age, they often score \< 27 points
- •without having dementia)
- •\- Clinical Dementia Rating (CDR) \= 0\.0 points, Cognitive impairment group:
- •\- MMSE: 20\-28 points inclusively
Exclusion Criteria
- •Clinical diagnosis of severe AD
- •Severe head trauma, with loss of consciousness
- •Brain tumour (past, present)
- •Schizophrenia, bipolar disorder, or recurrent psychotic disorders
- •Stroke resulting in physical impairment
- •Non\-AD neurodegenerative disorders (e.g. Huntington disease, cortical basal
- •degeneration, multiple system atrophy, CreutzfeldtJacob disease, primary
- •progressive aphasia, Parkinson\*s disease, diffuse Lewy body disease,
- •frontotemporal dementia, primary vascular dementia)
- •Epilepsy, currently using antiepileptic drugs (AEDs)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
Protective factors for dementia in subjects aged 90 years and olderThe protective factors of Alzheimer's disease in subjects aged 90 years and olderTherapeutic area: Diseases [C] - Nervous System Diseases [C10]EUCTR2016-002635-15-NLVU Medical Center120
Completed
Not Applicable
The 90+ StudyAlzheimer, dementia, ageing, oldest oldNL-OMON25600VU University Medical Center74
Completed
Not Applicable
The effect of resilience education on stress of mothersStress.Other stressful life events affecting family and householdIRCT2016083129621N1Vice chancellor for research,Yasuj University of Medical Sciences105
Recruiting
Not Applicable
Resilience in caregivers of patients with advanced cancersHealth Condition 1: C00-D49- NeoplasmsCTRI/2017/03/008151Jayita Deodhar75
Recruiting
Phase 1
Research on the Effectiveness of Resilience Interventions in the Air Self-Defense Forcestress, mentalhealthD040701JPRN-jRCT1030220150Kitano Masato1,400