MedPath
Found 468 clinical trials|View Analysis
Sort by:
Need a comprehensive medical report on "Acute Myeloid Leukemia (AML)"?
Analyze the latest clinical research and treatment options
Summarize scientific findings from medical journals

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

First Posted Date
2015-04-15
Last Posted Date
2024-08-07
Lead Sponsor
University Hospital, Angers
Target Recruit Count
3100
Registration Number
NCT02416388
Locations
🇫🇷

CH Amiens Hôpital Sud, Amiens, France

🇫🇷

CHU Angers, Angers, France

🇫🇷

CH Victor Dupouy, Argenteuil, France

and more 53 locations

A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer

Phase 1
Completed
Conditions
Acute Myeloid Leukemia (AML)
Multiple Myeloma
Non-Hodgkins Lymphoma
Cancer
Non-Small Cell Lung Cancer
Prostate Cancer
Small Cell Lung Cancer
Breast Cancer
Interventions
Drug: ABBV-075
First Posted Date
2015-03-18
Last Posted Date
2019-11-29
Lead Sponsor
AbbVie
Target Recruit Count
128
Registration Number
NCT02391480
Locations
🇺🇸

Scottsdale Healthcare /ID# 132963, Scottsdale, Arizona, United States

🇺🇸

City of Hope /ID# 154053, Duarte, California, United States

🇺🇸

UC Davis Comp Cancer Ctr /ID# 154644, Sacramento, California, United States

and more 7 locations

Study of Ibrutinib in Subjects With Acute Myeloid Leukemia

Phase 2
Terminated
Conditions
Acute Myeloid Leukemia (AML)
Interventions
Drug: Ibrutinib+Azacitidine
First Posted Date
2015-01-30
Last Posted Date
2018-08-14
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
36
Registration Number
NCT02351037
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

UC Davis Medical Center, Sacramento, California, United States

🇺🇸

The University of Chicago Medical Center, Chicago, Illinois, United States

and more 6 locations

SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction

Phase 3
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
Drug: SGI-110 (guadecitabine)
Drug: Treatment Choice
First Posted Date
2015-01-28
Last Posted Date
2024-08-27
Lead Sponsor
Astex Pharmaceuticals, Inc.
Target Recruit Count
815
Registration Number
NCT02348489
Locations
🇺🇸

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

🇺🇸

Scripps Cancer Center, La Jolla, California, United States

🇺🇸

University of Southern California, Los Angeles, California, United States

and more 124 locations

Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia (AML)

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2015-01-22
Last Posted Date
2019-11-15
Lead Sponsor
Gilead Sciences
Target Recruit Count
148
Registration Number
NCT02343939
Locations
🇺🇸

UCLA, Los Angeles, California, United States

🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Loyola University Medical Center, Maywood, Illinois, United States

and more 14 locations

Idarubicin Plus Cytarabine (IA) vs IA Plus Cladribine (IAC) as Induction Regimen to Treat Initially Diagnosed Acute Myeloid Leukemia (AML)

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: IA regimen
Drug: IAC regimen
First Posted Date
2014-12-23
Last Posted Date
2024-07-30
Lead Sponsor
The First Affiliated Hospital of Soochow University
Target Recruit Count
618
Registration Number
NCT02323022
Locations
🇨🇳

The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

A Study Assessing tOTX015 in Combination With Azacitidine (AZA) or AZA Single Agent in Patients With Newly-diagnosed Acute Myeloid Leukemia (AML) Not Candidate for Standard Intensive Induction Therapy (SIIT)

Phase 1
Withdrawn
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2014-12-01
Last Posted Date
2016-09-01
Lead Sponsor
Oncoethix GmbH, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Registration Number
NCT02303782

Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission

Phase 2
Terminated
Conditions
Leukemia
Interventions
First Posted Date
2014-11-27
Last Posted Date
2018-10-03
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
5
Registration Number
NCT02302846
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

1336GCC: Study of Erwinaze for Treatment of Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2014-11-05
Last Posted Date
2018-03-12
Lead Sponsor
Ashkan Emadi
Target Recruit Count
5
Registration Number
NCT02283190
Locations
🇺🇸

University of Maryland Greenebaum Cancer Center, Baltimore, Maryland, United States

Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment

Phase 2
Withdrawn
Conditions
Acute Lymphoblastic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Interventions
First Posted Date
2014-10-21
Last Posted Date
2018-03-14
Lead Sponsor
Jazz Pharmaceuticals
Registration Number
NCT02269579
Locations
🇺🇸

Ronald Reagan UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Shands Cancer Hospital @ University of Florida, Gainesville, Florida, United States

🇺🇸

Franciscan St. Francis Health, Indianapolis, Indiana, United States

and more 2 locations

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

Product

Company

Legal

© 2025 MedPath, Inc. All rights reserved.