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Risk Adapted Treatment for Primary Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Leukemia, Myelocytic, Acute
Interventions
Other: Autologous peripheral blood stem cell transplantation.
Other: Allogeneic matched related or unrelated donor transplant.
Other: CD34+ selection.
Other: Mylotarg purging before autologous PBSC transplantation
First Posted Date
2012-11-08
Last Posted Date
2012-11-08
Lead Sponsor
Grupo Cooperativo de Estudio y Tratamiento de las Leucemias Agudas y Mielodisplasias
Target Recruit Count
862
Registration Number
NCT01723657
Locations
🇪🇸

Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain

🇪🇸

ICO Hospital Universitari de Bellvitge, L'Hospitalet del Llobregat, Barcelona, Spain

🇪🇸

Hospital A Coruña, A Coruña, Coruña, Spain

and more 18 locations

Decitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion for Elderly Patients With Acute Myeloid Leukemia(AML)

Phase 1
Completed
Conditions
MDS
AML
Interventions
Drug: Granulocyte colony-stimulating factor
Other: HLA haploidentical mononuclear cells infusion
First Posted Date
2012-09-21
Last Posted Date
2016-02-25
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
29
Registration Number
NCT01690507
Locations
🇨🇳

Navy General Hospital, Beijing, Beijing, China

🇨🇳

Chinese PLA General Hospital, Beijing, China

AML-MDS Novel Prognostic Tests Clinical Study

Completed
Conditions
Myelodysplastic Syndrome (MDS)
Acute Myeloid Leukemia (AML)
First Posted Date
2012-09-14
Last Posted Date
2022-11-08
Lead Sponsor
Nova Scotia Health Authority
Target Recruit Count
11
Registration Number
NCT01685619
Locations
🇨🇦

Tom Baker Cancer Centre, Calgary, Alberta, Canada

🇨🇦

Vancouver General Hospital, Vancouver, British Columbia, Canada

🇨🇦

CancerCare Manitoba, Winnipeg, Manitoba, Canada

and more 3 locations

Phase I Study of Milatuzumab for Graft Versus Host Disease

Phase 1
Terminated
Conditions
GVHD (Acute or Chronic)
Multiple Myeloma (MM)
Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia (CLL or SLL)
Myelodysplastic Syndrome
Non-Hodgekin Lymphoma (NHL-both Follicular & Diffuse Large Cell)
Acute Myeloid or Lymphoblastic Leukemia (AML or ALL)
Chronic Myelogenous Leukemia (CML)
Interventions
First Posted Date
2012-08-13
Last Posted Date
2021-08-19
Lead Sponsor
Gilead Sciences
Target Recruit Count
12
Registration Number
NCT01663766
Locations
🇺🇸

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2012-08-10
Last Posted Date
2018-07-30
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
19
Registration Number
NCT01662505
Locations
🇯🇵

Boehringer Ingelheim Investigational Site, Yoshida-gun, Fukui, Japan

Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Phase 1
Completed
Conditions
Neutropenia
Acute Myeloid Leukemia (AML)
Myeldysplastic Syndrome (MDS)
Chronic Myelomonocytic Leukemia
Bone Marrow Diseases
First Posted Date
2012-06-27
Last Posted Date
2019-12-17
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Target Recruit Count
4
Registration Number
NCT01629082
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

A Phase Ib Study of Panobinostat (LBH589) in Combination With 5-Azacitidine for Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML) Patients

Phase 1
Completed
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes (MDS)
Chronic Myelomonocytic Leukemia (CMML)
Interventions
First Posted Date
2012-06-07
Last Posted Date
2020-12-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
10
Registration Number
NCT01613976
Locations
🇯🇵

Novartis Investigative Site, Kyoto, Japan

Prospective Study on Severe Infections on Acute Myeloid Leukemia (AML) Patients

Terminated
Conditions
AML
Adult
First Posted Date
2012-04-04
Last Posted Date
2022-10-12
Lead Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto
Target Recruit Count
144
Registration Number
NCT01570465
Locations
🇮🇹

U.O. di Medicina Interna - ASUR Marche 8 - Ospedale Civile, Civitanova Marche, Ancona, Italy

🇮🇹

S.O.C. di Ematologia - Azienda Ospedaliera - SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

🇮🇹

Azienda Ospedaliera - Nuovo Ospedale "Torrette", Ancona, Italy

and more 43 locations

The Efficacy of Azacitidine +/- Lenalidomide in High-risk Myelodysplastic Syndrome (MDS)and Acute Myeloid Leukemia (AML) With Del(5q).

Phase 2
Conditions
Myelodysplastic Syndrome
Acute Myelogenous Leukemia
Interventions
First Posted Date
2012-03-16
Last Posted Date
2012-03-16
Lead Sponsor
Nordic MDS Group
Target Recruit Count
72
Registration Number
NCT01556477
Locations
🇸🇪

Lars Möllgård, Stockholm, Sweden

Temozolomide Plus Vorinostat in Relapse/Refractory Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Acute Myeloid Leukemia With 11q23-abnormality in Relapse
Interventions
First Posted Date
2012-03-09
Last Posted Date
2018-08-09
Lead Sponsor
Steven E. Coutre
Target Recruit Count
23
Registration Number
NCT01550224
Locations
🇺🇸

Stanford University Medical Center, Stanford, California, United States

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