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Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

Phase 2
Withdrawn
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Interventions
First Posted Date
2012-01-30
Last Posted Date
2016-12-29
Lead Sponsor
Cornerstone Pharmaceuticals
Registration Number
NCT01520805
Locations
🇺🇸

Cornerstone Pharmaceuticals, Inc, Cranbury, New Jersey, United States

Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

Phase 2
Recruiting
Conditions
Leukemia
Interventions
First Posted Date
2012-01-24
Last Posted Date
2025-08-07
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
160
Registration Number
NCT01515527
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Phase I/II Trial: BIBF 1120 Added to Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia (AML)

Phase 1
Conditions
Acute Myeloid Leukemia
Interventions
Drug: triple kinase inhibitor BIBF1120
First Posted Date
2011-12-08
Last Posted Date
2013-12-11
Lead Sponsor
University Hospital Muenster
Target Recruit Count
140
Registration Number
NCT01488344
Locations
🇩🇪

Universitätsklinikum Münster, Medizinische Klinik und Poliklinik A, Münster, Germany

Study of OCV-501 in Patients With Acute Myeloid Leukemia (AML) (Extension From Study 311-10-001)

Phase 1
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2011-11-21
Last Posted Date
2021-03-02
Lead Sponsor
Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
18
Registration Number
NCT01475370
Locations
🇯🇵

National Cancer Center, Tokyo, Japan

Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Phase 3
Completed
Conditions
Disorder Related to Bone Marrow Transplantation
Leukemia
Transplantation Infection
Interventions
First Posted Date
2011-11-15
Last Posted Date
2021-12-16
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
256
Registration Number
NCT01471444
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2011-11-09
Last Posted Date
2019-02-12
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
13
Registration Number
NCT01468467
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

and more 2 locations

Accuracy Testing of the Chromosomal Aberration and Gene Mutation Markers of the AMLProfiler

Terminated
Conditions
Refractory Anemia With Excess of Blasts (RAEB)
Acute Promyelocytic Leukemia (APL)
Acute Myeloid Leukemia (AML)
First Posted Date
2011-11-01
Last Posted Date
2013-05-29
Lead Sponsor
Skyline Diagnostics BV
Target Recruit Count
264
Registration Number
NCT01463410
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

James Cancer Hospital, Columbus, Ohio, United States

🇩🇪

University Hospital Ulm, Ulm, Germany

and more 2 locations

Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)

Phase 1
Conditions
Myelodysplastic Syndrome
Acute Myeloid Leukemia
Interventions
First Posted Date
2011-10-13
Last Posted Date
2018-03-20
Lead Sponsor
Johann Wolfgang Goethe University Hospital
Target Recruit Count
62
Registration Number
NCT01451268
Locations
🇩🇪

University Hospital Düsseldorf, Düsseldorf, Germany

🇩🇪

University Hospital Essen, Essen, Germany

🇩🇪

University Hospital Frankfurt, Frankfurt am Main, Germany

and more 3 locations

Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS

Phase 2
Terminated
Conditions
Acute Myeloid Leukemia (AML)
Leukemia
Myelodysplastic Syndromes (MDS)
Interventions
First Posted Date
2011-09-28
Last Posted Date
2018-01-03
Lead Sponsor
Stanford University
Target Recruit Count
33
Registration Number
NCT01442714
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Evaluation of KX2-391 in Elderly Subjects With Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Acute Myelogenous Leukemia
Interventions
First Posted Date
2011-07-20
Last Posted Date
2015-12-07
Lead Sponsor
Kinex Pharmaceuticals Inc.
Target Recruit Count
24
Registration Number
NCT01397799
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

🇺🇸

Weill Cornell Medical College, New York, New York, United States

🇺🇸

Thomas Jefferson University, Philadelphia, Pennsylvania, United States

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