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A Study of Azacitidine and Venetoclax in People With Acute Myeloid Leukemia (AML)

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2025-01-14
Last Posted Date
2025-08-01
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
30
Registration Number
NCT06773208
Locations
🇺🇸

Memorial Sloan Kettering at Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale, New Jersey, United States

and more 4 locations

Evaluation of the Safety and Efficacy of Human CI-135 (FLT3) Targeted CAR-T Cells Injection for Subjects with Relapsed/Refractory Acute Myeloid Leukemia

Early Phase 1
Recruiting
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2025-01-06
Last Posted Date
2025-01-07
Lead Sponsor
Hrain Biotechnology Co., Ltd.
Target Recruit Count
7
Registration Number
NCT06760260
Locations
🇨🇳

First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

Azacitidine Combined with Donor Lymphocyte Infusion for Acute Myeloid Leukemia Post-transplant Relapse Prevention.

Phase 2
Not yet recruiting
Conditions
Acute Myeloid Leukemia (AML)
Relapse
Interventions
First Posted Date
2025-01-01
Last Posted Date
2025-01-17
Lead Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Target Recruit Count
51
Registration Number
NCT06754540

A Clinical Study to Explore the Safety and Efficacy of CT0991 in Relapsed/Refractory Acute Myeloid Leukemia

Phase 1
Recruiting
Conditions
Relapsed/Refractory Acute Myeloid Leukemia(AML)
Interventions
Drug: CAR-T cells( chimeric antigen receptor T cells)
First Posted Date
2024-11-29
Last Posted Date
2025-02-10
Lead Sponsor
He Huang
Target Recruit Count
24
Registration Number
NCT06709131
Locations
🇨🇳

The first affiliated hospital of medical college of zhejiang university, Hangzhou, Zhejiang, China

Assessing Refractoriness and Infectious Survival Events in AML

Completed
Conditions
Acute Myeloid Leukemia (AML)
First Posted Date
2024-11-28
Last Posted Date
2024-11-28
Lead Sponsor
Hospices Civils de Lyon
Target Recruit Count
280
Registration Number
NCT06709235
Locations
🇫🇷

Hopital Lyon Sud, Pierre Bénite, France

Ivosidenib as Post-HSCT Maintenance for AML

Phase 2
Not yet recruiting
Conditions
IDH1 Mutation
Acute Myeloid Leukemia (AML)
Hematopoietic Stem Cell Transplant (HSCT)
Interventions
Drug: Placebo
First Posted Date
2024-11-27
Last Posted Date
2025-07-20
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
75
Registration Number
NCT06707493
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Induced Pluripotent Stem Cells Derived Natural Killer Cells Therapy for Refractory and Relaps Acute Myelogenous Leukemia

Early Phase 1
Not yet recruiting
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2024-11-22
Last Posted Date
2024-11-22
Lead Sponsor
Guangzhou Ruixin Biotechnological Co., LTD
Target Recruit Count
10
Registration Number
NCT06702098
Locations
🇨🇳

Guangzhou Ruixin Biotechnology Co., Ltd, Guangzhou city, Guangdong Province, China, China

Creation of a Biocollection of Patients with Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored At the Nantes University Hospital

Not yet recruiting
Conditions
Acute Myeloid Leucemia
High-risk Myelodysplastic Syndrome (MDS)
Acute Lymphoid Leukemia
First Posted Date
2024-11-08
Last Posted Date
2024-11-11
Lead Sponsor
Nantes University Hospital
Target Recruit Count
1000
Registration Number
NCT06681363
Locations
🇫🇷

Nantes University Hospital, Nantes, France

Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2024-11-07
Last Posted Date
2025-08-24
Lead Sponsor
Sutro Biopharma, Inc.
Target Recruit Count
24
Registration Number
NCT06679582
Locations
🇺🇸

Childrens Hospital of Los Angeles, Los Angeles, California, United States

🇺🇸

Lucile Packard Childrens Hospital-Stanford, Palo Alto, California, United States

🇺🇸

Children's Hospital of Colorado, Aurora, Colorado, United States

and more 33 locations

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

Phase 2
Recruiting
Conditions
Relapsed or Refractory Acute Myeloid Leukemia (AML)
Interventions
Drug: Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) regimen
First Posted Date
2024-10-28
Last Posted Date
2025-06-18
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Target Recruit Count
52
Registration Number
NCT06660368
Locations
🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

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