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Clofarabine, Idarubicin, and Cytarabine Combination in Acute Myeloid Leukemia (AML) Induction

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-12-03
Last Posted Date
2018-10-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
63
Registration Number
NCT01025154
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients

Phase 2
Suspended
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Interventions
First Posted Date
2009-11-10
Last Posted Date
2015-02-10
Lead Sponsor
BioMAS Ltd
Target Recruit Count
12
Registration Number
NCT01010373
Locations
🇮🇱

Sheba Medical Center, Tel Hashomer, Israel

Efficacy Study for AC220 to Treat Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: Compound AC220
First Posted Date
2009-10-05
Last Posted Date
2019-12-11
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
333
Registration Number
NCT00989261
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

and more 82 locations

Maintenance Therapy in Acute Myeloid Leukemia (AML) Patients

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-08-12
Last Posted Date
2015-06-19
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
24
Registration Number
NCT00957385
Locations
🇨🇦

University Health Network, Princess Margaret Hospital, Toronto, Ontario, Canada

CLAG Gleevec in Relapsed or Refractory Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Leukemia
Interventions
Drug: CLAG Regimen
First Posted Date
2009-08-10
Last Posted Date
2014-06-27
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Target Recruit Count
38
Registration Number
NCT00955916
Locations
🇺🇸

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).

Phase 1
Completed
Conditions
Acute Myeloid Leukemia
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndromes
Interventions
First Posted Date
2009-07-27
Last Posted Date
2020-08-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
113
Registration Number
NCT00946647
Locations
🇺🇸

Georgia Health Sciences University Dept. of MCG, Augusta, Georgia, United States

🇺🇸

Goshen Center for Cancer Care IU Cancer Center, Indianapolis, Indiana, United States

🇺🇸

University of Kansas Hospital and Medical Center SC - Univ KS, Kansas City, Kansas, United States

and more 6 locations

Treatment of Acute Myeloid Leukemia (AML) in Adults 50 to 70 Years, Study of Two Anthracyclines and the Interest of Maintenance Treatment With Interleukin 2

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: chemotherapy (Aracytine + Daunorubicin)
First Posted Date
2009-07-02
Last Posted Date
2009-07-02
Lead Sponsor
Acute Leukemia French Association
Target Recruit Count
420
Registration Number
NCT00931138
Locations
🇫🇷

CH, Versailles, France

🇫🇷

Hopital Percy, Clamart, France

🇫🇷

CHU, Rouen, France

and more 6 locations

A Randomized Study of Gemtuzumab Ozogamicin (GO) With Daunorubicine and Cytarabine in Untreated Acute Myeloid Leukemia (AML) Aged of 50-70 Years Old

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: conventional chemotherapy (AraC + Daunorubicin),
First Posted Date
2009-06-25
Last Posted Date
2013-07-11
Lead Sponsor
Acute Leukemia French Association
Target Recruit Count
280
Registration Number
NCT00927498
Locations
🇫🇷

CH, Valenciennes, France

🇫🇷

Hopital Avicenne, Bobigny, France

🇫🇷

Hopital Percy, Clamart, France

and more 7 locations

A Study of Clofarabine in Older Patients With Acute Myeloid Leukemia (AML) for Whom Chemotherapy Is Not Suitable

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-06-19
Last Posted Date
2015-04-01
Lead Sponsor
Genzyme, a Sanofi Company
Target Recruit Count
69
Registration Number
NCT00924443

Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalities

Phase 2
Completed
Conditions
Myelodysplastic Syndromes
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2009-06-08
Last Posted Date
2013-04-24
Lead Sponsor
King's College London
Target Recruit Count
40
Registration Number
NCT00915785
Locations
🇬🇧

King's College Hospital NHS Foundation Trust, London, United Kingdom

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