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Efficacy of 5-azacytidine Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-06-05
Last Posted Date
2012-12-17
Lead Sponsor
University Hospital Muenster
Target Recruit Count
214
Registration Number
NCT00915252
Locations
🇩🇪

RWTH Aachen, Medizinische Klinik IV, Aachen, Germany

🇩🇪

Sozialstiftung Bamberg, Klinikum am Bruderwald, Med. Klinik V, Bamberg, Germany

🇩🇪

Klinikum Bayreuth, Medizinische Klinik IV, Bayreuth, Germany

and more 24 locations

Induction, Consolidation and Intensification Therapy for Patients Younger Than 66 Years With Previously Untreated CD33 Positive Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: FLAIMy - Fluda, Ida, Ara-C, Mylotarg
First Posted Date
2009-05-27
Last Posted Date
2014-05-06
Lead Sponsor
University Hospital, Udine, Italy
Target Recruit Count
130
Registration Number
NCT00909168
Locations
🇮🇹

University Hospital, Udine, Udine, Italy

Study Evaluating Sorafenib Added to Standard Primary Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Less Than 60 Years of Age

Phase 2
Completed
Conditions
Acute Myeloid Leukemia (AML)
Interventions
Drug: placebo
First Posted Date
2009-05-06
Last Posted Date
2016-02-05
Lead Sponsor
Technische Universität Dresden
Target Recruit Count
276
Registration Number
NCT00893373
Locations
🇩🇪

Sozialstiftung Bamberg Klinikum am Bruderwald, Bamberg, Germany

🇩🇪

Klinikum Bayreuth, Bayreuth, Germany

🇩🇪

Charite Campus Benjamin Franklin, Berlin, Germany

and more 6 locations

Study of Chemotherapy in Combination With All-trans Retinoic Acid (ATRA) With or Without Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemia (AML) and Mutant Nucleophosmin-1 (NPM1) Gene Mutation

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: Gemtuzumab Ozogamicin (Mylotarg)
Drug: standard chemotherapy
First Posted Date
2009-05-06
Last Posted Date
2023-02-27
Lead Sponsor
University of Ulm
Target Recruit Count
600
Registration Number
NCT00893399
Locations
🇦🇹

Medizinische Universitäts Graz, Graz, Austria

🇦🇹

Universitätsklinikum Innsbruck, Innsbruck, Austria

🇦🇹

Krankenhaus der Barmherzigen Schwestern Linz Betriebsgesellschaft m.b.H., Linz, Austria

and more 57 locations

Phase 1-2 of Azacitidine + Lenalidomide for Previously Untreated Elderly Patients With Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Acute Myeloid Leukemia (AML)
Adult Acute Myeloblastic Leukemia
Interventions
First Posted Date
2009-04-30
Last Posted Date
2018-06-18
Lead Sponsor
Stanford University
Target Recruit Count
45
Registration Number
NCT00890929
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q

Phase 2
Conditions
Myelodysplastic Syndrome
Chronic Myelomonocytic Leukemia
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-04-22
Last Posted Date
2015-04-24
Lead Sponsor
Groupe Francophone des Myelodysplasies
Target Recruit Count
85
Registration Number
NCT00885508
Locations
🇫🇷

CH Angers, Angers, France

🇫🇷

hopital Victor Dupouy, Argenteuil, France

🇫🇷

Centre Hospitalier de La Cote Basque, Bayonne, France

and more 22 locations

Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
First Posted Date
2009-04-13
Last Posted Date
2009-04-13
Lead Sponsor
Acute Leukemia French Association
Target Recruit Count
473
Registration Number
NCT00880243

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL)

Phase 2
Completed
Conditions
ALL
BAL
MDS
AML
First Posted Date
2009-03-17
Last Posted Date
2017-07-19
Lead Sponsor
Nantes University Hospital
Target Recruit Count
30
Registration Number
NCT00863148
Locations
🇫🇷

Hôpital Edouard Herriot, Lyon, France

🇫🇷

Institut Paoli Calmettes, Marseille, France

🇫🇷

Nantes University hospital, Nantes, France

and more 3 locations

Efficacy of Gemtuzumab Ozogamycin for Patients Presenting an Acute Myeloid Leukemia (AML) With Intermediate Risk

Phase 3
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Drug: gemtuzumab ozogamycin
First Posted Date
2009-03-12
Last Posted Date
2017-01-27
Lead Sponsor
Nantes University Hospital
Target Recruit Count
327
Registration Number
NCT00860639
Locations
🇫🇷

CH Pays d'Aix, Aix, France

🇫🇷

CHU Amiens, Amiens, France

🇫🇷

CHRU Angers, Angers, France

and more 25 locations

Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)

Phase 1
Completed
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2009-02-25
Last Posted Date
2016-03-01
Lead Sponsor
University of Ulm
Target Recruit Count
89
Registration Number
NCT00850382
Locations
🇦🇹

Universitätsklinikum Innsbruck, Innsbruck, Austria

🇦🇹

Krankenhaus der Barmherzigen Schwestern, Linz, Austria

🇦🇹

Elisabethinen Krankenhaus, Linz, Austria

and more 47 locations

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