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Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)

Recruiting
Conditions
Primary Immune Thrombocytopenia
Interventions
Diagnostic Test: Plasma RNA isolation, qPCR analysis of micro RNA
Diagnostic Test: estimation of serum level of IL2
Diagnostic Test: estimation of serum level of IL17
First Posted Date
2022-05-12
Last Posted Date
2023-04-12
Lead Sponsor
Sohag University
Target Recruit Count
2
Registration Number
NCT05371743
Locations
🇪🇬

Sohag University, Sohag, Egypt

Dynamic Multiomics Evaluation of Anti-HER2 and Immunotherapy in HER2 Positive Gastric Cancer

Not Applicable
Recruiting
Conditions
HER2 Positive Advanced Gastric Cancer
Interventions
Procedure: Samples including blood and tissue collection
Procedure: CTC detection
Procedure: ctDNA detection
Procedure: 10×genomics single cell RNA sequence
Procedure: Whole exon sequence
Procedure: Proteomics detection
First Posted Date
2022-04-27
Last Posted Date
2022-04-27
Lead Sponsor
Peking University
Target Recruit Count
100
Registration Number
NCT05348161
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

Strata EXPress™: A Study Using StrataEXP™ to Identify RNA-Expression Biomarkers in Advanced Cancer Patients

Withdrawn
Conditions
Cancer
First Posted Date
2022-04-05
Last Posted Date
2024-02-26
Lead Sponsor
Strata Oncology
Registration Number
NCT05312307

Clinical Evaluation of Rapid RNA Test for Covid-19

Not Applicable
Completed
Conditions
COVID-19
Interventions
Diagnostic Test: rapid RT-LAMP test to detect SARS-COV-2 RNA
First Posted Date
2022-04-04
Last Posted Date
2022-04-04
Lead Sponsor
University of Southampton
Target Recruit Count
369
Registration Number
NCT05308550
Locations
🇬🇧

Watford General Hospital, Watford, Hertfordshire, United Kingdom

Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe

Completed
Conditions
HIV Infections
RNA Virus Infections
Virus Disease
Syphilis
Neisseria Gonorrheae Infection
Chlamydia Trachomatis Infection
Blood-Borne Infections
Infections
Sexually Transmitted Diseases
Communicable Disease
Interventions
Drug: PrEP
Device: STI testing
Behavioral: Assisted partner notification
Diagnostic Test: Acute HIV testing
First Posted Date
2022-04-01
Last Posted Date
2023-10-05
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
249
Registration Number
NCT05307991
Locations
🇲🇼

Bwaila STI clinic, Lilongwe, Malawi

Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study

Phase 2
Completed
Conditions
Virus Diseases
Hemorrhagic Fevers, Viral
Hemorrhagic Fever, Ebola
RNA Virus Infections
Filoviridae Infections
Immunologic Factors
Physiological Effects of Drugs
Ebola
Infections
Mononegavirales Infections
Interventions
First Posted Date
2022-03-17
Last Posted Date
2025-05-11
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
133
Registration Number
NCT05284097
Locations
🇸🇱

EBOVAC Kambia 1 clinic, Kambia, Sierra Leone

GM03 - Platelet RNA Signatures of Aspirin

Early Phase 1
Completed
Conditions
Platelet Aggregation Inhibitors
Aspirin
Ticagrelor
RNA
Interventions
First Posted Date
2022-03-14
Last Posted Date
2022-03-14
Lead Sponsor
Duke University
Target Recruit Count
135
Registration Number
NCT05278637
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

Identify microRNAs in Cachexia in Pancreatic Carcinoma

Recruiting
Conditions
Resectable Pancreatic Adenocarcinoma
Interventions
Other: Pancreatic cancer microRNA and messenger RNA expression.
First Posted Date
2022-03-11
Last Posted Date
2025-02-11
Lead Sponsor
University of Oklahoma
Target Recruit Count
100
Registration Number
NCT05275075
Locations
🇺🇸

Stephenson Cancer Center, Oklahoma City, Oklahoma, United States

Novel RNA-nanoparticle Vaccine for the Treatment of Early Melanoma Recurrence Following Adjuvant Anti-PD-1 Antibody Therapy

Phase 1
Suspended
Conditions
Melanoma
Interventions
Biological: Autologous total tumor mRNA loaded DOTAP liposome vaccine
First Posted Date
2022-03-03
Last Posted Date
2025-04-04
Lead Sponsor
University of Florida
Target Recruit Count
18
Registration Number
NCT05264974
Locations
🇺🇸

University of Florida, Gainesville, Florida, United States

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Completed
Conditions
Neonatal Sepsis
Viral Infection
Neonatal Death
Neonatal Herpes Simplex Infection
Neonatal Infection
Newborn; Infection
Neonatal HSV Infection
Herpes Simplex Virus Infection
First Posted Date
2022-02-07
Last Posted Date
2022-12-28
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
159
Registration Number
NCT05226949
Locations
🇩🇰

Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen, Denmark

🇩🇰

Department of Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark

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