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The Clinical Impact of Integrated Behavioral Health Techniques in Patients With Fibromyalgia

Not Applicable

Not yet recruiting

Conditions: Fibromyalgia

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Mayo Clinic

Target Recruit Count: 300

Registration Number: NCT06988761

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer: an Open-label, Single-arm, Multicentre, Phase 2 Study

Not Applicable

Not yet recruiting

Conditions: Non-Muscle Invasive Bladder Cancer

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Target Recruit Count: 50

Registration Number: NCT06990061

Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs)

Not Applicable

Recruiting

Conditions: Occupational Health
Stress
Burnout
Mental Health Conditions
Sickness Absence

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: VU University of Amsterdam

Target Recruit Count: 148

Registration Number: NCT06989398

Locations: 🇳🇱
Vrije Universiteit Amsterdam, Amsterdam, Netherlands

A Study Designed to Assess the Mass Balance Recovery, Absorption, Metabolism, Excretion of [14C]AZD5462 and the Absolute Bioavailability of AZD5462

Phase 1

Not yet recruiting

Conditions: Heart Failure

Interventions: Drug: AZD5462 film-coated tablet
Drug: [14C]AZD5462 Solution for Infusion
Drug: [14C]AZD5462 Oral Solution

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: AstraZeneca

Target Recruit Count: 8

Registration Number: NCT06989983

Locations: 🇬🇧
Research Site, Ruddington, United Kingdom

Cognitive Remediation for Autistic Adolescents

Early Phase 1

Completed

Conditions: Autism Spectrum Disorder

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: South London and Maudsley NHS Foundation Trust

Target Recruit Count: 20

Registration Number: NCT06989151

Locations: 🇬🇧
King's College London, London, United Kingdom

A Phase 1/2a Study to Evaluate Single Intraarticular Injections of 3 Dose Levels of SYN321 and Placebo in Patients With Symptomatic Knee Osteoarthritis

Phase 1

Not yet recruiting

Conditions: Osteoarthritis of Knee

Interventions: Drug: SYN321 and placebo

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Synartro AB

Target Recruit Count: 36

Registration Number: NCT06989645

Locations: 🇸🇪
Cinical Trial Consultants AB, Uppsala, Sweden

Probiotic Intervention on Body Weight

Not Applicable

Not yet recruiting

Conditions: Obesity
Homeostasis
Weight Loss
Probiotic Intervention

Interventions: Behavioral: Energy-restricted nutritional and lifestyle intervention
Behavioral: General lifestyle and nutritional education
Dietary Supplement: Placebo
Drug: semaglutide
Dietary Supplement: Probiotic

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Chinese Academy of Sciences

Target Recruit Count: 140

Registration Number: NCT06989177

Locations: 🇨🇳
Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China

Acupuncture for Postherpetic Neuralgia

Not Applicable

Not yet recruiting

Conditions: Postherpetic Neuralgia ( PHN )

Interventions: Device: Electroacupuncture (Hans-100A, Nanjing Jisheng Medical Technology, China)
Drug: Pharmacotherapy：① Pregabalin ( Lyrica™ ，Pfizer Inc. America) ② Methylcobalamin ( Mecobalamin tablets， Weicai (China) Pharmaceutical Co., Ltd， China）
Procedure: Streitberger Placebo Needle Set ( Asiamed )

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Dexiong Han

Target Recruit Count: 207

Registration Number: NCT06990854

Locations: 🇨🇳
The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

Effect of EIT-guided PEEP On Clinical Outcomes in ARDS Patients: a Pilot Randomized Controlled Trial

Not Applicable

Not yet recruiting

Conditions: ARDS (Acute Respiratory Distress Syndrome)

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Southeast University, China

Target Recruit Count: 60

Registration Number: NCT06990477

The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up

Not Applicable

Not yet recruiting

Conditions: Dental Caries

First Posted Date: 2025-05-25

Last Posted Date: 2025-05-25

Lead Sponsor: Cairo University

Target Recruit Count: 80

Registration Number: NCT06990945

Locations: 🇪🇬
Faculty of Dentistry, Cairo University, Cairo, Egypt