Risperidone
- Generic Name
- Risperidone
- Brand Names
- Perseris, Risperdal, Rykindo, Uzedy, Okedi
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27FN4O2
- CAS Number
- 106266-06-2
- Unique Ingredient Identifier
- L6UH7ZF8HC
- Background
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).
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- Indication
Risperidone is indicated for the treatment of schizophrenia and irritability associated with autistic disorder. It is also indicated as monotherapy, or adjunctly with lithium or valproic acid, for the treatment of acute mania or mixed episodes associated with bipolar I disorder.
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- Associated Conditions
- Acute Mania, Irritability, Mixed manic depressive episode, Psychosis, Schizophrenia, Acute Manic episode, Agitated psychotic state
- Associated Therapies
- -
Treatment for First-Episode Schizophrenia
- Conditions
- First Posted Date
- 1999-11-03
- Last Posted Date
- 2012-01-13
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 125
- Registration Number
- NCT00000374
- Locations
- 🇺🇸
Bronx-Lebanon Hospital Center, Bronx, New York, United States
🇺🇸Hillside Hospital, Glen Oaks, New York, United States
Phase II Double Blind Placebo Controlled Trial of Risperidone in Tourette Syndrome
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 50
- Registration Number
- NCT00004393
Infusion Laboratory: Protocol 3 (Risperidone) - 4
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-11
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 13
- Registration Number
- NCT00000339
- Locations
- 🇺🇸
Friends Research Institute, Los Angeles, California, United States
Serotonin/Dopamine Antagonism of Cocaine Effect: 1 - 1
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2015-07-24
- Lead Sponsor
- Butler Hospital
- Registration Number
- NCT00000309
- Locations
- 🇺🇸
Brown University School of Medicine, Providence, Rhode Island, United States
Risperidone for the Treatment of Cocaine Dependence - 7
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-16
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000342
- Locations
- 🇺🇸
Friends Research Institute, Los Angeles, California, United States
Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-16
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000310
- Locations
- 🇺🇸
Brown University School of Medicine, Providence, Rhode Island, United States
Early Phase II Trials for Cocaine Medication Development - 1
- Conditions
- Interventions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-06-26
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 31
- Registration Number
- NCT00000317
- Locations
- 🇺🇸
NYS Psychiatric Institute, New York, New York, United States
Risperidone Treatment in Dually-Diagnosed Individuals - 2
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000267
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Risperidone for Treatment of Cocaine Dependence in Outpatients - 12
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000347
- Locations
- 🇺🇸
Friends Research Institute, Los Angeles, California, United States
Drug Development Updates
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