Risperidone
- Generic Name
- Risperidone
- Brand Names
- Perseris, Risperdal, Rykindo, Uzedy, Okedi
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27FN4O2
- CAS Number
- 106266-06-2
- Unique Ingredient Identifier
- L6UH7ZF8HC
- Background
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).
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- Indication
Risperidone is indicated for the treatment of schizophrenia and irritability associated with autistic disorder. It is also indicated as monotherapy, or adjunctly with lithium or valproic acid, for the treatment of acute mania or mixed episodes associated with bipolar I disorder.
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- Associated Conditions
- Acute Mania, Irritability, Mixed manic depressive episode, Psychosis, Schizophrenia, Acute Manic episode, Agitated psychotic state
- Associated Therapies
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A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis
- Conditions
- Interventions
- First Posted Date
- 2013-04-02
- Last Posted Date
- 2015-02-04
- Lead Sponsor
- Wei Hao
- Target Recruit Count
- 120
- Registration Number
- NCT01822730
- Locations
- 🇨🇳
The Second Xiangya Hospital of Central University, Changsha, Hunan, China
A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis
- Conditions
- Interventions
- First Posted Date
- 2013-03-19
- Last Posted Date
- 2015-02-04
- Lead Sponsor
- Wei Hao
- Target Recruit Count
- 50
- Registration Number
- NCT01813643
- Locations
- 🇨🇳
The Second Xiangya Hospital of Central University, Changsha, Hunan, China
Omega-3 Dietary Supplements in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2013-02-07
- Last Posted Date
- 2017-02-01
- Lead Sponsor
- Delbert Robinson
- Target Recruit Count
- 50
- Registration Number
- NCT01786239
- Locations
- 🇺🇸
The Zucker Hillside Hospital, Glen Oaks, New York, United States
Bioequivalence Study of Risperidone Tablet 1 mg Under Fasting Condition
- First Posted Date
- 2012-11-06
- Last Posted Date
- 2012-11-06
- Lead Sponsor
- IPCA Laboratories Ltd.
- Target Recruit Count
- 48
- Registration Number
- NCT01722201
- Locations
- 🇮🇳
Accutest Research Lab (I) Pvt. Ltd., Ahmedabad, Gujarat, India
A Study of the Combination of Multiple Doses of RO5285119 With a Single Dose of Risperidone in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2012-10-17
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 24
- Registration Number
- NCT01708616
Multiple Ascending Dose Study of the Safety, Tolerability, Pharmacokinetic/Efficacy
- First Posted Date
- 2012-09-03
- Last Posted Date
- 2018-10-23
- Lead Sponsor
- Indivior Inc.
- Target Recruit Count
- 45
- Registration Number
- NCT01677377
- Locations
- 🇺🇸
Woodland International Research Group, Inc., Little Rock, Alaska, United States
🇺🇸Ocean View Psychiatric Health Facility, Long Beach, California, United States
Clozapine for Cannabis Use in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2012-07-13
- Last Posted Date
- 2020-05-05
- Lead Sponsor
- Dartmouth-Hitchcock Medical Center
- Target Recruit Count
- 49
- Registration Number
- NCT01639872
- Locations
- 🇺🇸
Pacific Research Partners, Oakland, California, United States
🇺🇸University of North Carolina/UNC Center for Excellence in Community Mental Health, Raleigh, North Carolina, United States
🇺🇸CNS Network Inc, Garden Grove, California, United States
A Long-Term Study of MP-214 in Patients With Chronic Phase or Elderly Schizophrenia
- First Posted Date
- 2012-06-22
- Last Posted Date
- 2021-04-13
- Lead Sponsor
- Mitsubishi Tanabe Pharma Corporation
- Target Recruit Count
- 125
- Registration Number
- NCT01625897
A Study to Evaluate the Efficacy and Safety of Risperidone (R064766) in Children and Adolescents With Irritability Associated With Autistic Disorder
- Conditions
- Interventions
- First Posted Date
- 2012-06-21
- Last Posted Date
- 2015-10-15
- Lead Sponsor
- Janssen Pharmaceutical K.K.
- Target Recruit Count
- 39
- Registration Number
- NCT01624675
Efficacy and Safety Study of Iloperidone Virus Risperidone to Treat Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2012-06-20
- Last Posted Date
- 2013-11-19
- Lead Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Target Recruit Count
- 260
- Registration Number
- NCT01623713
- Locations
- 🇨🇳
Sixth Hospital of Peking University, Peking, Beijing, China
Drug Development Updates
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