Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate.
Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy greens. Magnesium is an important enzyme cofactor and is essential to several metabolic processes. Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein synthesis among several other functions.
Despite the importance of magnesium and its availability via several food sources, an estimated 56 to 68% of adults who live in developed, western countries do not meet the recommended daily intake (RDI) of magnesium. Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).
Healthy levels of magnesium can be achieved through a well balanced diet, but if food sources are insufficient, magnesium supplements can be used to prevent and treat magnesium deficiencies.
In medicine, various magnesium salts may be used in laxative and antacid products. For example, magnesium citrate is available over-the-counter and may be used to manage occasional constipation. Magnesium sulfate may be used on its own or with total parenteral nutrition to treat hypomagnesemia. Magnesium sulfate is also indicated to prevent seizures in pregnant women with pre-eclampsia, and to manage seizures associated with eclampsia.
The Children's Hospital and the Institute of Child Health, Multan, Punjab, Pakistan
KalVista Investigative Site, Tokyo, Japan
Konkuk University Medical Center, Seoul, Korea, Republic of
Arthrosi Investigative Site (402), Taichung, Taiwan
Arthrosi Investigative Site (400), Taipei, Taiwan
Arthrosi Investigative Site (403), Taipei, Taiwan
Neumora Investigator Site, Bellevue, Washington, United States
Ain Shams University, Cairo, Egypt
JCRC-Joint Clinical Research Centre, Kampala, Uganda
IDRC-Infectious Disease Research Collaboration, IDRC Tororo Hospital Station Road, Tororo, Uganda
Simbec-Orion, Merthyr Tydfil, United Kingdom
LLC "Clinic Zvezdnaya", Saint Petersburg, Russian Federation
St. Petersburg State Budgetary Healthcare Institution "City Polyclinic № 112", Saint Petersburg, Russian Federation
LLC "Research Center Eco-Safety", Saint Petersburg, Russian Federation
Advocate Christ Medical Center Emergency Department (ACMC ED), Oak Lawn, Illinois, United States
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