Selegiline
- Generic Name
- Selegiline
- Brand Names
- Emsam, Zelapar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H17N
- CAS Number
- 14611-51-9
- Unique Ingredient Identifier
- 2K1V7GP655
Overview
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Background
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Indication
Monotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression.
Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD)
- Major Depressive Disorder (MDD)
- Parkinson's Disease (PD)
Clinical Trials
FDA Approved Products
Singapore Approved Products
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