MedPath

Dinalbuphine sebacate

Generic Name
Dinalbuphine sebacate
Drug Type
Small Molecule
Chemical Formula
C52H68N2O10
CAS Number
311768-81-7
Unique Ingredient Identifier
464OXX39Y6
Background

Dinalbuphine sebacate is under investigation in clinical trial NCT02468128 (A Study of Intramuscular Sebacoyl Dinalbuphine Ester for Post-Hemorrhoidectomy Pain Management).

Postoperative Pain Management on Patients Undergoing Lung Tumor Resection

Not yet recruiting
Conditions
Postoperative Pain
Lung Tumor
Lung Cancer
Interventions
Drug: Analgesic injectables
Drug: Enteral analgesics
First Posted Date
2024-05-03
Last Posted Date
2024-05-03
Lead Sponsor
China Medical University Hospital
Target Recruit Count
400
Registration Number
NCT06397807

A Novel, Potent and Non-addictive Analgesic of Combinations for Knee Replacement Moderate to Severe Pain Management

Phase 2
Conditions
Pain, Postoperative
Interventions
Drug: Naldebain + SafeTynadol
First Posted Date
2023-05-06
Last Posted Date
2023-07-27
Lead Sponsor
Sinew Pharma Inc.
Target Recruit Count
36
Registration Number
NCT05842733
Locations
🇨🇳

Taipei Veterans General Hospital, Taipei City, Beitou District, Taiwan

Postoperative Pain Management on Uvulopalatopharyngoplasty Patients

Phase 4
Not yet recruiting
Conditions
Obstructive Sleep Apnea-hypopnea Syndrome
Pain, Postoperative
Pain, Acute
Interventions
Other: Routine practice
First Posted Date
2023-04-24
Last Posted Date
2023-04-25
Lead Sponsor
Li-Jen Hsin
Target Recruit Count
78
Registration Number
NCT05825495

Naldebain® Extended-release Injection After Cesarean Section in Pain Management

Conditions
Post Operative Pain
Caesarean Section
Analgesia
Interventions
First Posted Date
2022-07-06
Last Posted Date
2022-07-06
Lead Sponsor
Tri-Service General Hospital
Target Recruit Count
20
Registration Number
NCT05446311

Postoperative Pain Management of Caesarean Section

Recruiting
Conditions
Postoperative Pain
Caesarean Section
Analgesia
Interventions
Drug: Intravenous patient-control analgesia
First Posted Date
2021-08-18
Last Posted Date
2025-05-09
Lead Sponsor
Mackay Memorial Hospital
Target Recruit Count
100
Registration Number
NCT05009771
Locations
🇨🇳

MacKay Memorial Hospital, Taipei, Taiwan

🇨🇳

MacKay Memorial Hospital Tamsui Branch, New Taipei City, Taiwan

Naldebain for Pain Management of Laparoscopic Cholecystectomy

Phase 2
Completed
Conditions
Pain, Postoperative
Pain, Chronic
Cholecystitis
Quality of Life
Interventions
Drug: Placebo solution
First Posted Date
2021-03-22
Last Posted Date
2022-04-20
Lead Sponsor
E-DA Hospital
Target Recruit Count
80
Registration Number
NCT04808544
Locations
🇨🇳

E-Da Hospital, Yanchao, Kaohsiung, Taiwan

Naldebain for Pain Control After Bariatric Surgery

Phase 2
Conditions
Pain, Postoperative
Pain, Chronic
Bariatric Surgery
Obesity
Pharmacokinetics
Interventions
Drug: Placebo solution
First Posted Date
2020-12-03
Last Posted Date
2021-12-28
Lead Sponsor
E-DA Hospital
Target Recruit Count
60
Registration Number
NCT04651361
Locations
🇨🇳

E-Da Hospital, Yanchao, Kaohsiung, Taiwan

A Bioavailability Study of NALDEBAIN ER Injection and Nalbuphine Injection in Healthy Volunteers.

Phase 1
Completed
Conditions
Health
Interventions
First Posted Date
2020-02-05
Last Posted Date
2021-11-19
Lead Sponsor
Lumosa Therapeutics Co., Ltd.
Target Recruit Count
24
Registration Number
NCT04256434
Locations
🇺🇸

WCCT Global Inc., Cypress, California, United States

NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis

Phase 4
Conditions
Postoperative Pain
Interventions
Drug: Morpine
First Posted Date
2019-02-26
Last Posted Date
2019-02-26
Lead Sponsor
China Medical University Hospital
Target Recruit Count
40
Registration Number
NCT03854851
Locations
🇨🇳

China Medical University & Hospital, Taichung, Taiwan

Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic Cholecystectomy

Phase 4
Completed
Conditions
Pain, Postoperative
Interventions
First Posted Date
2018-10-19
Last Posted Date
2020-07-16
Lead Sponsor
Cathay General Hospital
Target Recruit Count
44
Registration Number
NCT03713216
Locations
🇨🇳

Cathay General Hospital, Taipei, Taiwan

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