Carbetocin
- Generic Name
- Carbetocin
- Brand Names
- Duratocin
- Drug Type
- Small Molecule
- Chemical Formula
- C45H69N11O12S
- CAS Number
- 37025-55-1
- Unique Ingredient Identifier
- 88TWF8015Y
- Background
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
- Indication
Used to control postpartum hemorrhage and bleeding after giving birth.
- Associated Conditions
- Postpartum Haemorrhage (PPH), Uterine Atony
Cardiac Changes After Effective Dose Carbetocin for Elective Caesarian Section
- First Posted Date
- 2025-04-27
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Jordan Leitch
- Target Recruit Count
- 200
- Registration Number
- NCT06946589
- Locations
- 🇨🇦
Kingston Health Sciences Centre, Kingston, Ontario, Canada
Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human Myometrium
- Conditions
- Postpartum Hemorrhage (Primary)
- Interventions
- First Posted Date
- 2025-04-16
- Last Posted Date
- 2025-04-16
- Lead Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT06930391
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Effects of Carbetocin and Oxytocin Used in Cesarean Sections on Postoperative Pain
- First Posted Date
- 2024-11-18
- Last Posted Date
- 2025-03-24
- Lead Sponsor
- Ankara City Hospital Bilkent
- Target Recruit Count
- 120
- Registration Number
- NCT06692621
- Locations
- 🇹🇷
Ankara Bilkent City Hospital, Ankara, Turkey
OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome
- First Posted Date
- 2024-05-20
- Last Posted Date
- 2025-05-04
- Lead Sponsor
- ACADIA Pharmaceuticals Inc.
- Target Recruit Count
- 160
- Registration Number
- NCT06420297
- Locations
- 🇩🇪
KJF Klinik Josefinum gGmbH, Augsburg, Germany
🇺🇸Children's of Alabama, Birmingham, Alabama, United States
🇺🇸Phoenix Children's Hospital, Phoenix, Arizona, United States
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
- First Posted Date
- 2024-03-27
- Last Posted Date
- 2025-01-22
- Lead Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Target Recruit Count
- 160
- Registration Number
- NCT06333340
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
- Conditions
- Postpartum Hemorrhage
- Interventions
- First Posted Date
- 2024-02-29
- Last Posted Date
- 2025-02-26
- Lead Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT06285409
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women
- Conditions
- Obesity, MaternalPost Partum Hemorrhage
- Interventions
- First Posted Date
- 2024-01-22
- Last Posted Date
- 2024-01-22
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT06217354
- Locations
- 🇪🇬
Shaimaa El Shemy, Giza, Cairo, Egypt
Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome
- Conditions
- Hyperphagia in Prader-Willi Syndrome
- Interventions
- Drug: Placebo
- First Posted Date
- 2023-12-15
- Last Posted Date
- 2025-04-03
- Lead Sponsor
- ACADIA Pharmaceuticals Inc.
- Target Recruit Count
- 170
- Registration Number
- NCT06173531
- Locations
- 🇺🇸
Indiana University Hospital, Indianapolis, Indiana, United States
🇫🇷Centre Hospitalier Universitaire (CHU) de Toulouse - Hôpital des Enfants, Toulouse, France
🇺🇸Children's of Alabama, Birmingham, Alabama, United States
Carbetocin in the Prevention of Primary Postpartum Haemorrhage
- First Posted Date
- 2023-12-07
- Last Posted Date
- 2023-12-07
- Lead Sponsor
- Ministry of Health and Population, Egypt
- Target Recruit Count
- 244
- Registration Number
- NCT06159959
- Locations
- 🇪🇬
Kasr- Alainy Hospitals, Cairo, Egypt
Evaluating Efficacy of Intravenous Carbetocin Versus Intramyometrial Injection of Adrenaline in Reducing Blood Loss
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Egymedicalpedia
- Target Recruit Count
- 62
- Registration Number
- NCT05986266
- Locations
- 🇪🇬
Faculty of medicine, Cairo University, Cairo, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.