MedPath

Volrustomig

Generic Name
Volrustomig

A Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (IVOLGA)

Phase 2
Recruiting
Conditions
Locally Advanced Cervical Cancer
Interventions
First Posted Date
2025-04-24
Last Posted Date
2025-04-24
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT06943833
Locations
🇷🇺

Research Site, Yekaterinburg, Russian Federation

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Phase 2
Recruiting
Conditions
Metastatic Colorectal Cancer
Interventions
Drug: FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan)
First Posted Date
2025-01-27
Last Posted Date
2025-05-15
Lead Sponsor
AstraZeneca
Target Recruit Count
120
Registration Number
NCT06792695
Locations
🇬🇧

Research Site, Wirral, United Kingdom

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Phase 2
Recruiting
Conditions
Cervical Cancer
Head and Neck Squamous Cell Carcinoma
Interventions
First Posted Date
2024-08-02
Last Posted Date
2025-03-06
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT06535607
Locations
🇨🇳

Research Site, Wuhan, China

Volrustomig Priming Regimens Exploratory Phase II Platform Study

Phase 2
Recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-06-07
Last Posted Date
2025-04-25
Lead Sponsor
AstraZeneca
Target Recruit Count
120
Registration Number
NCT06448754
Locations
🇮🇹

Research Site, Verona, Italy

🇨🇳

Research Site, Taipei, Taiwan

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC

Early Phase 1
Recruiting
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
Biological: Rilvegostomig
Biological: Sabestomig
Combination Product: AZD9592 + Rilvegostomig
Combination Product: AZD9592 + Volrustomig
Combination Product: AZD9592 + Sabestomig
Combination Product: AZD9592 + Pembrolizumab
First Posted Date
2024-04-16
Last Posted Date
2025-01-20
Lead Sponsor
Presage Biosciences
Target Recruit Count
15
Registration Number
NCT06366451
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

🇺🇸

UC Davis, Sacramento, California, United States

🇺🇸

Montefiore Medical Center, Bronx, New York, United States

and more 4 locations

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Phase 3
Recruiting
Conditions
Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions
First Posted Date
2023-11-13
Last Posted Date
2024-10-03
Lead Sponsor
AstraZeneca
Target Recruit Count
1145
Registration Number
NCT06129864
Locations
🇻🇳

Research Site, Vinh, Vietnam

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

Phase 3
Recruiting
Conditions
Unresectable Pleural Mesothelioma
Interventions
First Posted Date
2023-10-24
Last Posted Date
2025-04-24
Lead Sponsor
AstraZeneca
Target Recruit Count
600
Registration Number
NCT06097728
Locations
🇬🇧

Research Site, Taunton, United Kingdom

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

Phase 3
Recruiting
Conditions
Locally Advanced Cervical Cancer
Interventions
First Posted Date
2023-10-12
Last Posted Date
2025-05-20
Lead Sponsor
AstraZeneca
Target Recruit Count
800
Registration Number
NCT06079671
Locations
🇹🇷

Research Site, Karsiyaka, Turkey

A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.

Phase 3
Recruiting
Conditions
Metastatic Non-small Cell Lung Cancer
Interventions
First Posted Date
2023-08-09
Last Posted Date
2025-03-12
Lead Sponsor
AstraZeneca
Target Recruit Count
900
Registration Number
NCT05984277
Locations
🇬🇧

Research Site, Truro, United Kingdom

MEDI5752 in Patients With Mature Tertiary Lymphoid Structures Solid Tumors.

Phase 2
Not yet recruiting
Conditions
Advanced Solid Tumor
Interventions
First Posted Date
2023-06-05
Last Posted Date
2023-08-04
Lead Sponsor
Institut Bergonié
Target Recruit Count
102
Registration Number
NCT05888857
Locations
🇫🇷

Institut Bergonie, Bordeaux, France

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