Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

First Posted Date
2024-12-20
Last Posted Date
2024-12-20
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Target Recruit Count
24
Registration Number
NCT06745882
Locations
🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

First-line Treatment with RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)

First Posted Date
2024-12-12
Last Posted Date
2024-12-12
Lead Sponsor
Qilu Hospital of Shandong University
Target Recruit Count
110
Registration Number
NCT06730373
Locations
🇨🇳

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

🇨🇳

Binzhou Medical University Hospital, Binzhou, Shandong, China

🇨🇳

Shengli Oilfield Central Hospital, Dongying, Shandong, China

and more 16 locations

Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC

First Posted Date
2024-12-10
Last Posted Date
2024-12-10
Lead Sponsor
Beijing Tongren Hospital
Target Recruit Count
50
Registration Number
NCT06725498
Locations
🇨🇳

Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing, Beijing, China

Nimotuzumab Combined With Sintilimab and Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma

First Posted Date
2024-12-05
Last Posted Date
2024-12-05
Lead Sponsor
The First Affiliated Hospital of Zhengzhou University
Target Recruit Count
112
Registration Number
NCT06718205
Locations
🇨🇳

Feng Wang, Zhengzhou, Henan, China

Phase Ⅱ Clinical Study of Surufatinib Combined With Gemcitabine and Cisplatin Plus Durvalumab/Pembrolizumab Regimen in the Treatment of Advanced Biliary Tract Cancer

First Posted Date
2024-11-27
Last Posted Date
2024-11-27
Lead Sponsor
Dai, Guanghai
Target Recruit Count
35
Registration Number
NCT06708858
Locations
🇨🇳

Chinese PLA General Hospital, Beijing, Beijing, China

Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist(Diphenhydramine)in Advanced and Metastatic Non-Small Cell Lung Cancer

First Posted Date
2024-11-26
Last Posted Date
2024-12-16
Lead Sponsor
Tianjin Medical University Cancer Institute and Hospital
Target Recruit Count
430
Registration Number
NCT06704620
Locations
🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma

First Posted Date
2024-11-26
Last Posted Date
2024-11-26
Lead Sponsor
Centre Leon Berard
Target Recruit Count
460
Registration Number
NCT06706401
Locations
🇫🇷

Centre Léon Bérard, Lyon, France

The Minimalist Trial-2

First Posted Date
2024-11-22
Last Posted Date
2024-11-22
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
153
Registration Number
NCT06702033
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

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