Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Adebrelimab Plus Apatinib for Maintenance Therapy of Extensive Small Cell Lung Cancer

First Posted Date
2024-06-28
Last Posted Date
2024-12-20
Lead Sponsor
Yunpeng Liu
Target Recruit Count
38
Registration Number
NCT06480864
Locations
🇨🇳

The First Hospital of China Medical University, Shenyang, China

Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer

First Posted Date
2024-06-20
Last Posted Date
2024-07-08
Lead Sponsor
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Target Recruit Count
80
Registration Number
NCT06465563
Locations
🇨🇳

The First Affiliated Hospital,Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

First Posted Date
2024-06-13
Last Posted Date
2024-11-05
Lead Sponsor
Coherus Biosciences, Inc.
Target Recruit Count
100
Registration Number
NCT06457503
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)

First Posted Date
2024-06-11
Last Posted Date
2024-11-15
Lead Sponsor
Bayer
Target Recruit Count
278
Registration Number
NCT06452277
Locations
🇨🇳

Fujian Cancer Hospital, Fuzhou, Fujian, China

🇨🇳

Hunan Cancer Hospital, Changsha, Hunan, China

🇨🇳

Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China

and more 241 locations

Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors

First Posted Date
2024-06-06
Last Posted Date
2024-06-06
Lead Sponsor
Qilu Pharmaceutical Co., Ltd.
Target Recruit Count
360
Registration Number
NCT06446388
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

First Posted Date
2024-06-06
Last Posted Date
2024-06-06
Lead Sponsor
Sichuan University
Target Recruit Count
30
Registration Number
NCT06446726

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-06-06
Last Posted Date
2024-12-17
Lead Sponsor
Zachary Zumsteg
Target Recruit Count
50
Registration Number
NCT06445114
Locations
🇺🇸

Cedars-Sinai Cancer at Beverly Hills (THO), Beverly Hills, California, United States

🇺🇸

Cedars Sinai Medical Center, Los Angeles, California, United States

🇺🇸

CS Cancer at Valley Oncology Medical Group, Tarzana, California, United States

and more 1 locations
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