MedPath

Anlotinib

Generic Name
Anlotinib
Drug Type
Small Molecule
Chemical Formula
C23H22FN3O3
CAS Number
1058156-90-3
Unique Ingredient Identifier
GKF8S4C432
Background

Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.

Indication

用于治疗非小细胞肺癌、结直肠癌、肾癌、软组织肉瘤、甲状腺癌、胃癌等。

用于无法手术的局部晚期或转移性甲状腺髓样癌患者的治疗。

Safety and Efficacy of Amlotinib in the Treatment of Recurrent Craniopharyngioma

Phase 1
Recruiting
Conditions
Craniopharyngiomas
Interventions
First Posted Date
2025-05-14
Last Posted Date
2025-05-14
Lead Sponsor
Nanfang Hospital, Southern Medical University
Target Recruit Count
57
Registration Number
NCT06970145
Locations
🇨🇳

Southern Medical University, Nanfang Hospital, Department of Neurosurgery, Guangzhou, Guangdong, China

Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction

Phase 4
Not yet recruiting
Conditions
Small Cell Lung Cancer
Interventions
First Posted Date
2025-04-30
Last Posted Date
2025-04-30
Lead Sponsor
China Medical University, China
Target Recruit Count
31
Registration Number
NCT06951841
Locations
🇨🇳

The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China

Benmelstobart, Anlotinib and Chemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer

Phase 4
Not yet recruiting
Conditions
Extensive-stage Small Cell Lung Cancer
Interventions
First Posted Date
2025-04-17
Last Posted Date
2025-04-23
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
50
Registration Number
NCT06931145
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

GAPP Induction and Concurrent Chemoradiotherapy Followed by Toripalimab Maintenance for Nasopharyngeal Carcinoma.

Phase 2
Recruiting
Conditions
Nasopharyngeal Carcinoma
Interventions
First Posted Date
2025-02-28
Last Posted Date
2025-02-28
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
47
Registration Number
NCT06851247
Locations
🇨🇳

Sun yat-sen University Cancer Center, Guangzhou, Guangdong, China

A Prospective, Single-arm Clinical Study of Liposomal Mitoxantrone Combination Regimen in the Treatment of Relapsed and Refractory Solid Tumors in Children, Adolescents and Young Adults

Phase 2
Not yet recruiting
Conditions
Solid Tumors
Children
Adolescents
Interventions
First Posted Date
2025-01-07
Last Posted Date
2025-01-08
Lead Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Target Recruit Count
49
Registration Number
NCT06761417
Locations
🇨🇳

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China

Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion

Phase 2
Recruiting
Conditions
Solid Tumor
Precision Medicine
Interventions
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Tianjin Medical University Second Hospital
Target Recruit Count
300
Registration Number
NCT06739395
Locations
🇨🇳

Tianjin Medical Unversity Second Hospital, Tianjin, Tianjin, China

Neoadjuvant Therapy of Targeted Immunotherapy Combined With Chemotherapy for Locally Advanced HNSCC

Phase 2
Not yet recruiting
Conditions
Head and Neck Squamous Cell Carcinoma
Neoadjuvant Therapy
PD-L1
Anlotinib
Interventions
First Posted Date
2024-11-21
Last Posted Date
2024-11-21
Lead Sponsor
The First Affiliated Hospital with Nanjing Medical University
Target Recruit Count
45
Registration Number
NCT06699498
Locations
🇨🇳

The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma.

Phase 1
Not yet recruiting
Conditions
Osteosarcoma
Soft Tissue Sarcoma (STS)
Interventions
First Posted Date
2024-11-21
Last Posted Date
2024-11-21
Lead Sponsor
Hansoh BioMedical R&D Company
Target Recruit Count
448
Registration Number
NCT06699576

Clinical Trial of Eribulin in Combination with Anrotinib for HER-2 Negative Locally Advanced or Metastatic Breast Cancer

Phase 2
Not yet recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2024-11-07
Last Posted Date
2024-11-07
Lead Sponsor
The First Hospital of Jilin University
Target Recruit Count
40
Registration Number
NCT06678230
Locations
🇨🇳

Cancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin Province, China, Changchun, Jilin, China

Nal-IRI/5-FU/LV Chemotherapy Combined with PD-L1 Inhibitor and Multi-target Anti-angiogenic Small Molecule±SBRT As Second-line Therapy in Metastatic Pancreatic Cancer Patients

Phase 2
Not yet recruiting
Conditions
Advanced Metastatic Pancreatic Cancer
Interventions
First Posted Date
2024-10-28
Last Posted Date
2024-10-28
Lead Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Target Recruit Count
56
Registration Number
NCT06662006
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