L-Cycloserine

Generic Name
L-Cycloserine
Brand Names
Seromycin
Drug Type
Small Molecule
Chemical Formula
C3H6N2O2
CAS Number
339-72-0
Unique Ingredient Identifier
AK7DRB7FMO
Background

Antibiotic substance produced by Streptomyces garyphalus.

Indication

本品与其他抗结核药联合,用于经一线药物(如吡嗪酰胺、链霉素、异烟肼、利福平和乙胺丁醇)治疗失败的患者。本品还可用于治疗非结核分枝杆菌感染如鸟复合分枝杆菌病的治疗。

Associated Conditions
Pulmonary Tuberculosis (TB), Tuberculosis, Extrapulmonary, Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection
Associated Therapies
-

Effectiveness of D-Cycloserine as an Aid to Enhance Learning for Individuals With OCD Receiving Behavior Therapy

First Posted Date
2005-09-16
Last Posted Date
2012-07-16
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
33
Registration Number
NCT00182000

Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder

Not Applicable
Completed
Conditions
First Posted Date
2005-08-18
Last Posted Date
2009-08-26
Lead Sponsor
Hartford Hospital
Target Recruit Count
40
Registration Number
NCT00131339
Locations
🇺🇸

Center for Anxiety and Related Disorders at Boston University, Boston, Massachusetts, United States

🇺🇸

Hartford Hospital, Hartford, Connecticut, United States

Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia

First Posted Date
2005-08-09
Last Posted Date
2014-05-20
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
48
Registration Number
NCT00128401
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder

Not Applicable
Completed
Conditions
First Posted Date
2005-08-03
Last Posted Date
2009-07-29
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
50
Registration Number
NCT00126282
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Anxiety Disorders Center, The Institute of Living, Hartford, Connecticut, United States

D-cycloserine in the Management of Chronic Low Back Pain

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-08-01
Last Posted Date
2017-02-09
Lead Sponsor
Thomas J. Schnitzer
Target Recruit Count
41
Registration Number
NCT00125528
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
525
Registration Number
NCT00000796
Locations
🇺🇸

Montefiore Drug Treatment Ctr / Bronx Municipal Hosp, Bronx, New York, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

🇺🇸

Bronx Lebanon Hosp Ctr, Bronx, New York, United States

and more 18 locations

Trial of D-Cycloserine in Schizophrenia

Phase 3
Completed
Conditions
Interventions
First Posted Date
1999-11-03
Last Posted Date
2014-09-10
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
60
Registration Number
NCT00000371

Glycine and D-Cycloserine in Schizophrenia

First Posted Date
1999-11-03
Last Posted Date
2014-06-12
Lead Sponsor
Massachusetts General Hospital
Registration Number
NCT00000372
Locations
🇺🇸

Freedom Trail Clinic, Boston, Massachusetts, United States

Neurobiology of Opioid Dependence: 3 - 3

Phase 2
Withdrawn
Conditions
First Posted Date
1999-09-21
Last Posted Date
2016-05-06
Lead Sponsor
Yale University
Registration Number
NCT00000194
Locations
🇺🇸

VA Connecticut Healthcare System, New Haven, Connecticut, United States

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