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Hexamethylenetetramine

Generic Name
Hexamethylenetetramine
Brand Names
Hyophen, Mandelamine, Phosphasal, Urelle, Uribel, Urimar Reformulated Oct 2013, Urin DS, Urogesic Blue Reformulated Apr 2012, Ustell, Utira
Drug Type
Small Molecule
Chemical Formula
C6H12N4
CAS Number
100-97-0
Unique Ingredient Identifier
J50OIX95QV
Background

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).

Indication

For prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug is not used to treat infection and should only be used after appropriate eradication of infection with antimicrobial agents.

Associated Conditions
Urinary Tract Infection
Associated Therapies
-

A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain

Phase 3
Recruiting
Conditions
Interstitial Cystitis
Interventions
Drug: Multimodal Bundle Drugs
Other: Usual Urogynecologic care
Procedure: Operative Cystoscopy
Behavioral: Behavioral health consultation/therapy
Other: Pelvic floor physical therapy
Drug: Bladder Instillation
Drug: Vaginal estrogen
Drug: Methenamine
Drug: Amitriptyline/Gabapentin
First Posted Date
2022-12-21
Last Posted Date
2024-02-06
Lead Sponsor
Jocelyn Fitzgerald
Target Recruit Count
80
Registration Number
NCT05658874
Locations
🇺🇸

Magee Womens Hospital, Pittsburgh, Pennsylvania, United States

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