MedPath

Ilginatinib

Generic Name
Ilginatinib
Drug Type
Small Molecule
Chemical Formula
C21H20FN7
CAS Number
1239358-86-1
Unique Ingredient Identifier
56R994WX4L
Background

NS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.

Study to Assess Efficacy and Safety of NS-018 Compared to BAT in Patients With Myelofibrosis

Phase 2
Terminated
Conditions
Primary Myelofibrosis
Post-polycythemia Vera Myelofibrosis
Post-essential Thrombocythemia Myelofibrosis
Interventions
Drug: Best Available Therapy
First Posted Date
2021-04-22
Last Posted Date
2024-06-06
Lead Sponsor
NS Pharma, Inc.
Target Recruit Count
7
Registration Number
NCT04854096
Locations
🇺🇸

University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States

🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

🇩🇪

Universitaetsklinikum Halle (Saale), Halle, Germany

and more 48 locations

Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

Phase 1
Completed
Conditions
Primary Myelofibrosis
Post-Polycythemia Vera Myelofibrosis
Post-Essential Thrombocythemia Myelofibrosis
Interventions
First Posted Date
2011-08-26
Last Posted Date
2022-03-09
Lead Sponsor
NS Pharma, Inc.
Target Recruit Count
77
Registration Number
NCT01423851
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

UC San Diego Moores Cancer Center, San Diego, California, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 6 locations
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