Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance during clinical trials. It is currently not approved as a prescription product by the FDA, but is widely available over the counter.
Glucosamine is generally used over the counter in the symptomatic treatment of osteoarthritis and joint pain, frequently combined with chondroitin sulfate and/or ibuprofen.
Columbia University, New York, New York, United States
University of Utah Health Sciences Center, Salt Lake City, Utah, United States
*Indiana University School of Medicine, Indianapolis, Indiana, United States
*Case Western Reserve University, Beachwood, Ohio, United States
Arthritis Consultation Center, Dallas, Texas, United States
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