Teduglutide
- Generic Name
- Teduglutide
- Brand Names
- Gattex, Revestive
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 197922-42-2
- Unique Ingredient Identifier
- 7M19191IKG
- Background
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide is longer acting than endogeno...
- Indication
Teduglutide is indicated for the treatment of adults and pediatric patients 1 year of age and older with Short Bowel Syndrome (SBS) who are dependent on parenteral support.
- Associated Conditions
- Short Bowel Syndrome (SBS)
- Associated Therapies
- -
A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older
- First Posted Date
- 2021-08-30
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Takeda
- Target Recruit Count
- 3
- Registration Number
- NCT05027308
- Locations
- 🇯🇵
University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan
🇯🇵Kagoshiha University Hospital, Kagoshima, Japan
🇯🇵Tohoku University Hospital, Sendai, Miyagi, Japan
A Study of Teduglutide in Japanese People With Short Bowel Syndrome
- First Posted Date
- 2021-08-26
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- Takeda
- Target Recruit Count
- 120
- Registration Number
- NCT05023382
- Locations
- 🇯🇵
Takeda Selected Site, Tokyo, Japan
Bridging Intestinal Failure With Teduglutide - a Case Report
- Conditions
- First Posted Date
- 2021-06-07
- Last Posted Date
- 2021-06-07
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 1
- Registration Number
- NCT04916665
- Locations
- 🇦🇹
Medical University of Vienna, Vienna, Austria
Teduglutide in Short Bowel Syndrome Patients
- Conditions
- First Posted Date
- 2021-04-23
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 17
- Registration Number
- NCT04857801
Pediatric Teduglutide Registry
- First Posted Date
- 2021-04-05
- Last Posted Date
- 2023-12-11
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 142
- Registration Number
- NCT04832087
- Locations
- 🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States
Quality of Life in Patients With Short Bowel Syndrome Treated Without and With Teduglutide - a Prospective Nested Matched Pair Analysis
- Conditions
- Interventions
- First Posted Date
- 2021-02-01
- Last Posted Date
- 2021-02-01
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 40
- Registration Number
- NCT04733066
- Locations
- 🇩🇪
Charite University, Berlin, Germany, Berlin, Germany
A Study to Evaluate the Bioavailability of Teduglutide Administered Subcutaneously by Syringe Injection Versus Pen Injector in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2020-07-10
- Last Posted Date
- 2022-10-04
- Lead Sponsor
- Shire
- Target Recruit Count
- 64
- Registration Number
- NCT04465396
- Locations
- 🇺🇸
Celerion, Phoenix, Arizona, United States
Treatment of Patients With Teduglutide (GLP-2) for GVHD and Analysis of Paneth Cells of GVHD Patients
- First Posted Date
- 2020-03-02
- Last Posted Date
- 2023-11-29
- Lead Sponsor
- University of Freiburg
- Target Recruit Count
- 6
- Registration Number
- NCT04290429
- Locations
- 🇩🇪
Medical Center University of Freiburg, Freiburg, Baden Württemberg, Germany
Pilot Study to Investigate the Effect of Teduglutide on Temporary Ileostomy Function and Complications
- First Posted Date
- 2019-05-16
- Last Posted Date
- 2023-02-23
- Lead Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- Registration Number
- NCT03953170
- Locations
- 🇺🇸
Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
Therapeutic Approaches to Malnutrition Enteropathy
- Conditions
- Interventions
- First Posted Date
- 2018-10-23
- Last Posted Date
- 2021-09-27
- Lead Sponsor
- Queen Mary University of London
- Target Recruit Count
- 125
- Registration Number
- NCT03716115
- Locations
- 🇿🇼
Harare Central Hospital, Harare, Zimbabwe
🇿🇼Parirenyatwa Hospital, Harare, Zimbabwe
🇿🇲University Teaching Hospital, Nationalist Road, Lusaka, Zambia
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.